{"id":"W2989239947","doi":"10.7554/elife.29688.030","title":"Author response: Glutamate is required for depression but not potentiation of long-term presynaptic function","year":2017,"lang":"en","type":"peer-review","venue":"","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Discovery Centre","funders":"","keywords":"Neuroscience; Postsynaptic potential; Long-term potentiation; Glutamate receptor; Hebbian theory; Metaplasticity; Synaptic plasticity; Excitatory postsynaptic potential; Long-term depression; Synapse; Neurotransmitter; Chemistry; NMDA receptor; Biology; Inhibitory postsynaptic potential; Computer science; AMPA receptor; Receptor; Biochemistry; Artificial intelligence; Artificial neural network; Central nervous system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008903128,0.001009108,0.001130359,0.0004767008,0.001503262,0.001511081,0.001850392,0.003097455,0.1855804],"category_scores_gemma":[0.003316205,0.0007161539,0.0006672239,0.0008161339,0.0007629159,0.001580791,0.002009699,0.002360764,0.1021501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001617828,"about_ca_system_score_gemma":0.001972459,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003795033,"about_ca_topic_score_gemma":0.007229426,"domain_scores_codex":[0.9988738,0.00005300396,0.00007644939,0.0002589535,0.000546435,0.00019134],"domain_scores_gemma":[0.998605,0.0001709662,0.0001734118,0.0002243974,0.00050297,0.0003233015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002140806,0.0001675892,0.001929639,0.001356559,0.00006716229,0.001759606,0.0001855312,0.0008641742,0.09761157,0.006543896,0.8264021,0.06097146],"study_design_scores_gemma":[0.0007679874,0.0001770987,0.0125603,0.0005105393,0.00006317041,0.002001409,0.0008135754,0.002006119,0.1112893,0.008275719,0.861424,0.0001107606],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.09740289,0.01377058,0.05266348,0.1462158,0.08064168,0.0009594646,0.09644512,0.01268724,0.4992138],"genre_scores_gemma":[0.2735803,0.01373906,0.04053982,0.02331512,0.00446808,0.0009622927,0.07385591,0.003689073,0.5658503],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.1855804,"threshold_uncertainty_score":0.6208284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1725304406556601,"score_gpt":0.4404652548064545,"score_spread":0.2679348141507945,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}