{"id":"W2989368452","doi":"10.1128/aac.01711-19","title":"<i>In Vitro</i> Activity of Plazomicin Compared to Amikacin, Gentamicin, and Tobramycin against Multidrug-Resistant Aerobic Gram-Negative Bacilli","year":2019,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Shionogi; National Board of Medical Examiners; Samsung; University of Manitoba; Rush University; Hennepin County Medical Center; Infectious Diseases Society of America; TenNor Therapeutics; Singapore General Hospital; Mayo Clinic","keywords":"Amikacin; Tobramycin; Gentamicin; Aminoglycoside; Microbiology; Multiple drug resistance; Medicine; Biology; Antibiotics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001139583,0.0006526287,0.0007240922,0.000642567,0.000323446,0.0007492868,0.0005273975,0.0005545663,0.002503775],"category_scores_gemma":[0.001721243,0.0002489516,0.0007620447,0.0008182423,0.0004190363,0.0004896148,0.0004428206,0.0009086961,0.0004776992],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004044491,"about_ca_system_score_gemma":0.000414155,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002963161,"about_ca_topic_score_gemma":0.002355121,"domain_scores_codex":[0.9974015,0.00121712,0.0004692369,0.0002717013,0.0004318035,0.0002086927],"domain_scores_gemma":[0.9986431,0.0004679693,0.0002549426,0.000152622,0.0003687813,0.0001125463],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003199175,0.0008113102,0.005484947,0.0004470267,0.0001517229,0.0001288811,0.0001694999,0.001675788,0.9804744,0.0002145598,0.0006331265,0.006609635],"study_design_scores_gemma":[0.00009224022,0.01032565,0.02279076,0.00003987556,0.0001844636,0.0004187515,0.0001288159,0.0018597,0.9612749,0.00007174146,0.002776207,0.00003686796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831072,0.008286782,0.001814703,0.0002982449,0.0002033828,0.00009226263,0.002006884,0.00005646553,0.004134043],"genre_scores_gemma":[0.9915262,0.001931432,0.002360838,0.0001314411,0.000101383,0.00007813543,0.002683597,0.00002312165,0.001163898],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002963161,"threshold_uncertainty_score":0.008376002,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006614363540533755,"score_gpt":0.2357274644937919,"score_spread":0.2291131009532581,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}