{"id":"W2989436630","doi":"10.1182/blood-2019-122501","title":"Randomized, Open-Label, Non-Inferiority, Phase 3 Study of Subcutaneous (SC) Versus Intravenous (IV) Daratumumab (DARA) Administration in Patients (Pts) with Relapsed or Refractory Multiple Myeloma (RRMM): Body Weight Subgroup Analysis of Columba","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research; University of Calgary","funders":"","keywords":"Daratumumab; Medicine; Subgroup analysis; Internal medicine; Multiple myeloma; Oncology; Lenalidomide; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003709686,0.002109793,0.003665142,0.000600877,0.0005395105,0.001862114,0.001093957,0.001860241,0.008876115],"category_scores_gemma":[0.002618702,0.0007787921,0.004904822,0.0007093966,0.001090612,0.001119509,0.0006564663,0.0033447,0.001193985],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00127622,"about_ca_system_score_gemma":0.00201331,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001258746,"about_ca_topic_score_gemma":0.004441473,"domain_scores_codex":[0.9985429,0.0009177744,0.000067874,0.0001939271,0.0001038264,0.0001737727],"domain_scores_gemma":[0.9984562,0.0004399445,0.000417437,0.0001696765,0.0001303621,0.0003863766],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9773447,0.005562279,0.001237058,0.0006029387,0.00384148,0.00005788449,0.00008020471,0.0003425084,0.003801338,0.00007502784,0.0007716236,0.00628299],"study_design_scores_gemma":[0.9356822,0.05584446,0.003992847,0.0000396963,0.002196515,0.00005722219,0.00005164302,0.0005646822,0.0003503493,0.0001827077,0.001012197,0.00002559093],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9773617,0.006379772,0.001616508,0.001256795,0.0006099859,0.007870585,0.002422414,0.0002072005,0.002274964],"genre_scores_gemma":[0.9817603,0.001836062,0.001584674,0.001760306,0.0004755545,0.007272696,0.001643715,0.0000481994,0.003618515],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008876115,"threshold_uncertainty_score":0.02969354,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0251781818217981,"score_gpt":0.3245696725637161,"score_spread":0.299391490741918,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}