{"id":"W2989604191","doi":"10.1016/j.neulet.2019.134641","title":"Nuclear accumulation of GAPDH, GluA2 and p53 in post-mortem substantia nigral region of patients with Parkinson’s disease","year":2019,"lang":"en","type":"article","venue":"Neuroscience Letters","topic":"Molecular Biology Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Glyceraldehyde 3-phosphate dehydrogenase; Excitotoxicity; Neurodegeneration; Programmed cell death; Biology; AMPA receptor; Substantia nigra; Cell biology; Glutamate receptor; Apoptosis; Pathology; Neuroscience; Receptor; Medicine; Biochemistry; Disease; Dopamine; Dehydrogenase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004339149,0.00007119433,0.00007949203,0.00004836131,0.00001959718,0.000005339733,0.0001200698,0.00003762121,0.000001352272],"category_scores_gemma":[0.00001615748,0.00006159745,0.00002347588,0.0001169837,0.0001495486,0.000007164074,0.00004452171,0.00004067335,2.387405e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003577927,"about_ca_system_score_gemma":0.0000139394,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000130597,"about_ca_topic_score_gemma":0.000004849619,"domain_scores_codex":[0.999385,0.00002842329,0.0001226947,0.0002657211,0.00009047527,0.0001076572],"domain_scores_gemma":[0.9995967,0.00000362258,0.00009839168,0.0002315118,0.00003370743,0.00003608757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00006411781,0.00002788727,0.4546536,0.000006834126,7.092118e-7,8.770685e-7,0.000008407788,0.00002821424,0.5450079,0.00004041371,0.0000280554,0.0001329469],"study_design_scores_gemma":[0.0002906345,0.0002076502,0.9740867,0.0000108735,0.000004935476,0.000001249967,0.000005126373,0.0001370209,0.02413997,0.00000575068,0.001033783,0.0000762915],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989339,0.00001312277,0.0004211282,0.0003403265,0.00001943507,0.0002418317,0.00001214837,0.000004811381,0.0000133499],"genre_scores_gemma":[0.9985849,0.00002228517,0.0002023474,0.001140209,0.000004324605,0.00000545679,0.00002779435,0.000007599697,0.00000510831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5208679,"threshold_uncertainty_score":0.2511871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01101191516111628,"score_gpt":0.2432828545980444,"score_spread":0.2322709394369282,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}