{"id":"W2989628597","doi":"10.3747/co.26.5575","title":"Metastatic Colorectal Cancer: Therapeutic Options for Treating Refractory Disease","year":2019,"lang":"en","type":"review","venue":"Current Oncology","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Centre for Applied Research in Cancer Control; Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"Regorafenib; Medicine; Colorectal cancer; Oncology; Internal medicine; Refractory (planetary science); Cancer; Disease; Population; Chemotherapy; Intensive care medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004045551,0.000544031,0.000913505,0.00213298,0.0002508398,0.0008578043,0.0005287147,0.000591203,0.005786756],"category_scores_gemma":[0.0007190433,0.0001472797,0.0006008189,0.001496185,0.0003446233,0.001006483,0.0005627542,0.001550419,0.001896991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004132868,"about_ca_system_score_gemma":0.0007603745,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008312078,"about_ca_topic_score_gemma":0.002627736,"domain_scores_codex":[0.999836,0.00003773281,0.00002648854,0.00002482625,0.0000596265,0.00001540233],"domain_scores_gemma":[0.999716,0.0001434104,0.00004855471,0.000008181661,0.00006071476,0.00002319627],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000521455,0.00004277729,0.0001561153,0.01717649,0.00008010714,0.0001468158,0.00004918183,0.0002222594,0.000837353,0.002575304,0.02596189,0.9526995],"study_design_scores_gemma":[0.00001688592,0.00009190231,0.0006320999,0.007270668,0.0001286865,0.001294065,0.00006092217,0.00006673136,0.000224209,0.001493364,0.9887081,0.00001239552],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001107795,0.9980043,0.00009308739,0.0004385503,0.0001479866,0.000005199832,0.00002389387,0.000007588849,0.001168591],"genre_scores_gemma":[0.0006178509,0.9985146,0.0001168436,0.0002315559,0.0001179038,0.000004460795,0.00003082484,0.000001373025,0.0003646255],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005786756,"threshold_uncertainty_score":0.01935858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2891659468620973,"score_gpt":0.5164499974146433,"score_spread":0.2272840505525459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}