{"id":"W2989629712","doi":"10.3389/fphar.2019.01339","title":"Association Study of the Complement Component C4 Gene in Tardive Dyskinesia","year":2019,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; Centre for Addiction and Mental Health Foundation; National Alliance for Research on Schizophrenia and Depression; Genome Canada","keywords":"Tardive dyskinesia; C4A; Schizophrenia (object-oriented programming); Schizoaffective disorder; Etiology; Psychosis; Medicine; Psychiatry; Gene; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004899881,0.0001450846,0.0004519253,0.0002054774,0.00004696869,0.000002965775,0.0004216133,0.00009061379,0.001202012],"category_scores_gemma":[0.00001839466,0.0001224187,0.00006870977,0.0002397824,0.00004568932,0.00003840063,0.0002450192,0.000225792,0.00006099022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004722387,"about_ca_system_score_gemma":0.00004612619,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000307035,"about_ca_topic_score_gemma":0.0001711632,"domain_scores_codex":[0.9976292,0.001105014,0.0005603567,0.0002786764,0.0000822002,0.0003445355],"domain_scores_gemma":[0.9992495,0.0001275117,0.0003276461,0.0002321107,0.00005136775,0.00001185761],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001963946,0.001009586,0.8728929,0.00001842581,0.0003378683,0.000003162087,0.0008746327,0.0003956474,0.05489776,0.00001189139,0.06926289,0.00009885477],"study_design_scores_gemma":[0.009924979,0.0002367936,0.9650927,0.00001846229,0.000114341,0.000001740391,0.002630138,0.00008904396,0.01051091,0.00005589688,0.01117736,0.0001476504],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890018,0.000673273,0.00002032869,0.0003291059,0.007708359,0.001994046,0.00004935553,0.00001435468,0.0002094168],"genre_scores_gemma":[0.9991394,0.0000137795,0.00003714724,0.0001644796,0.00002376585,0.0001354379,0.00003901893,0.000009907462,0.0004370205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09219979,"threshold_uncertainty_score":0.999711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0101052246539949,"score_gpt":0.2640935284827419,"score_spread":0.253988303828747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}