{"id":"W2989710357","doi":"10.1016/j.chest.2019.11.019","title":"Is Mortality a Useful Primary End Point for Critical Care Trials?","year":2019,"lang":"en","type":"review","venue":"CHEST Journal","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"Kingston Health Sciences Centre; Queen's University","funders":"Southeastern Ontario Academic Medical Organization","keywords":"Medicine; End point; Outcome (game theory); Randomized controlled trial; Clinical endpoint; Clinical trial; Intensive care medicine; Mortality rate; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.02002825,0.001673113,0.01432616,0.002964546,0.0004696708,0.00457594,0.002199872,0.004039299,0.007970594],"category_scores_gemma":[0.06246947,0.001004022,0.005834958,0.002902653,0.001230379,0.003119854,0.001501962,0.00529616,0.001455784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001766815,"about_ca_system_score_gemma":0.004517424,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001477901,"about_ca_topic_score_gemma":0.004292618,"domain_scores_codex":[0.9885265,0.00623456,0.002856798,0.000726492,0.001412113,0.0002435526],"domain_scores_gemma":[0.9246113,0.06418563,0.006358363,0.0008503863,0.003346986,0.0006472783],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.003233869,0.00008777311,0.0006977209,0.3984216,0.01427204,0.00007331138,0.00009463675,0.0004446244,0.000293028,0.003169717,0.03587345,0.5433382],"study_design_scores_gemma":[0.01002497,0.002353616,0.004761098,0.5126456,0.08532788,0.0004323438,0.0003150176,0.001072321,0.0004645524,0.01346543,0.3689639,0.0001733999],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008195812,0.9975261,0.0001504314,0.001314687,0.0005546583,0.00003731828,0.00008724398,0.000008779179,0.0002387447],"genre_scores_gemma":[0.004482788,0.9869963,0.001408818,0.004764473,0.001752064,0.0002192275,0.0001397523,0.00001391242,0.0002227119],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9799718,"threshold_uncertainty_score":0.1059208,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.6019983021739507,"score_gpt":0.5376308475340839,"score_spread":0.06436745463986682,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}