{"id":"W2989729548","doi":"10.1111/age.12884","title":"Association of a <i>P2RX7</i> gene missense variant with brachycephalic dog breeds","year":2019,"lang":"en","type":"article","venue":"Animal Genetics","topic":"Human-Animal Interaction Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Australian Companion Animal Health Foundation; American Kennel Club Canine Health Foundation","keywords":"Missense mutation; Biology; Genetics; Sanger sequencing; Exon; Pedigree chart; Gene; Veterinary medicine; Mutation; Medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001456961,0.0001740941,0.0002177896,0.00004131529,0.00004532073,0.00002161053,0.0001367093,0.0001404582,0.000093628],"category_scores_gemma":[0.00003825627,0.0001587146,0.00008379568,0.0001046294,0.00003993689,0.000004380928,0.0001052193,0.0000930243,0.00008176862],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002822749,"about_ca_system_score_gemma":0.00005491052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002892794,"about_ca_topic_score_gemma":0.00007736809,"domain_scores_codex":[0.9988783,0.00005486919,0.0002658147,0.0003189539,0.0002370054,0.0002450364],"domain_scores_gemma":[0.9990822,0.0000250754,0.0002378444,0.0003011118,0.0002966452,0.00005711028],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002362652,0.00008440008,0.03566438,0.00002079488,0.000292076,0.00001009762,0.0001069078,0.00005673941,0.9605957,0.00003918315,0.002774973,0.0001184373],"study_design_scores_gemma":[0.001195641,0.003171188,0.0639085,0.00002243052,0.0001509342,0.0001523136,0.0002238636,0.000119109,0.863009,0.00001528038,0.06763267,0.0003990223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947482,0.0006808288,0.000134217,0.0001384009,0.0001095478,0.0001887351,0.00003108152,0.00001300898,0.003956022],"genre_scores_gemma":[0.9934898,0.0002270872,0.001470651,0.0003336543,0.000183188,0.000008491438,0.00003491174,0.00003298911,0.004219217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09758669,"threshold_uncertainty_score":0.6472193,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008990669459522666,"score_gpt":0.281342407687653,"score_spread":0.2723517382281303,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}