{"id":"W2989764345","doi":"10.1182/blood-2019-132405","title":"The QUAZAR AML-001 Maintenance Trial: Results of a Phase III International, Randomized, Double-Blind, Placebo-Controlled Study of CC-486 (Oral Formulation of Azacitidine) in Patients with Acute Myeloid Leukemia (AML) in First Remission","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta Hospital; Alberta Hospital Edmonton","funders":"","keywords":"Azacitidine; Medicine; Myeloid leukemia; Internal medicine; Placebo; Randomized controlled trial; Randomization; Leukemia; Oncology; Alternative medicine; Biology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00185889,0.001351459,0.001956536,0.0003045753,0.000360117,0.000741455,0.0008044412,0.001376293,0.004696517],"category_scores_gemma":[0.001264065,0.000411882,0.0008801298,0.0002988506,0.0009462856,0.000710097,0.0003116448,0.002196562,0.0007775101],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005775121,"about_ca_system_score_gemma":0.001077163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000487082,"about_ca_topic_score_gemma":0.001195501,"domain_scores_codex":[0.9995408,0.0002376986,0.00003210012,0.00009689931,0.0000343334,0.00005830803],"domain_scores_gemma":[0.9992449,0.000158573,0.0002104652,0.00005663783,0.00005055896,0.0002788431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9600264,0.008060267,0.0008299754,0.00074522,0.0006094362,0.00003798913,0.00006060372,0.0002640053,0.009756532,0.0000946304,0.0007712637,0.0187437],"study_design_scores_gemma":[0.9252229,0.07050498,0.002106078,0.00001961324,0.000457336,0.00004029167,0.0000129841,0.0002087045,0.0007666435,0.00006302711,0.0005885034,0.000008905713],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858565,0.00475326,0.0005776775,0.0006656526,0.0002537832,0.004359277,0.00140425,0.0001552769,0.001974343],"genre_scores_gemma":[0.9876814,0.002141631,0.001390035,0.0008408783,0.0003000172,0.003821646,0.001530291,0.00002690867,0.002267222],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004696517,"threshold_uncertainty_score":0.01571143,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01909008641973868,"score_gpt":0.3055970149617177,"score_spread":0.286506928541979,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}