{"id":"W2989764345","doi":"10.1182/blood-2019-132405","title":"The QUAZAR AML-001 Maintenance Trial: Results of a Phase III International, Randomized, Double-Blind, Placebo-Controlled Study of CC-486 (Oral Formulation of Azacitidine) in Patients with Acute Myeloid Leukemia (AML) in First Remission","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta Hospital; Alberta Hospital Edmonton","funders":"","keywords":"Azacitidine; Medicine; Myeloid leukemia; Internal medicine; Placebo; Randomized controlled trial; Randomization; Leukemia; Oncology; Alternative medicine; Biology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003251122,0.0002783569,0.001638183,0.0005603748,0.00004558089,0.00001662462,0.0004055205,0.0001595881,0.00001620423],"category_scores_gemma":[0.001086629,0.0001654765,0.0001774246,0.0006212206,0.000125297,0.0002188285,0.0001322926,0.0004177968,0.00000319485],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003832437,"about_ca_system_score_gemma":0.0004927466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001388332,"about_ca_topic_score_gemma":0.0006085883,"domain_scores_codex":[0.9956586,0.0003343306,0.00200809,0.0004382955,0.001182689,0.000377977],"domain_scores_gemma":[0.9961559,0.001163481,0.001199166,0.000674423,0.0007122002,0.00009482956],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.976177,0.01427792,0.005713778,0.00007132049,0.0008845706,0.00001993212,0.001370607,0.00009997115,0.0007852062,0.00005712052,0.0000967688,0.0004457815],"study_design_scores_gemma":[0.9866843,0.004168522,0.001268728,0.0005210724,0.0003976697,0.000003488853,0.0005810672,0.003586076,0.002560632,0.00002062325,0.00006015482,0.0001476568],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851899,0.00003847086,0.00002115762,0.0002511846,0.0001144531,0.01330136,0.00003875919,0.00001506223,0.001029644],"genre_scores_gemma":[0.9983276,0.0001086656,0.0001558771,0.00001454108,0.0000437052,0.0003859109,0.0001711033,0.00003593939,0.0007566569],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01313769,"threshold_uncertainty_score":0.6747935,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01909008641973868,"score_gpt":0.3055970149617177,"score_spread":0.286506928541979,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}