{"id":"W2989779760","doi":"10.1039/c9ob02509j","title":"Reversible control of RNA interference by siRNAzos","year":2019,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Tech University; Lakeridge Health","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Interference (communication); RNA interference; Azobenzene; RNA; Small interfering RNA; Chemistry; Computer science; Biochemistry; Telecommunications; Gene; Polymer; Channel (broadcasting); Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002577534,0.0003520179,0.000326978,0.0001763153,0.0001535251,0.0003889648,0.0005164059,0.000321675,0.00109875],"category_scores_gemma":[0.0002471711,0.0001777456,0.0002985508,0.0001414037,0.0003621921,0.0002592232,0.0002469271,0.0006309457,0.0003739059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000367157,"about_ca_system_score_gemma":0.0001531007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004818361,"about_ca_topic_score_gemma":0.0008860045,"domain_scores_codex":[0.9997106,0.00003040837,0.00002259663,0.00008726775,0.000109546,0.00003945981],"domain_scores_gemma":[0.9998338,0.00004837836,0.00005913195,0.00001890393,0.00002695721,0.00001284394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001498542,0.000003791999,0.00001661377,0.0000320849,0.000002911788,0.00001620913,0.000009481584,0.00003091324,0.9989641,0.0001515902,0.00002537065,0.000731997],"study_design_scores_gemma":[0.000004669551,0.00003685876,0.0001477791,0.000001337599,0.00000375082,0.00003831115,0.000003040569,0.0002463096,0.9977736,0.00002058627,0.001721124,0.000002565437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8849127,0.01053132,0.09068918,0.0003672094,0.0003084683,0.0003089404,0.0007561793,0.001108763,0.01101725],"genre_scores_gemma":[0.9700505,0.00341724,0.01793733,0.0001318618,0.00003737193,0.0001722946,0.000459051,0.0001246087,0.007669782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00109875,"threshold_uncertainty_score":0.003675699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003384586985363916,"score_gpt":0.1997478501480923,"score_spread":0.1963632631627284,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}