{"id":"W2989808997","doi":"10.1038/s41746-019-0191-0","title":"Artificial intelligence for precision medicine in neurodevelopmental disorders","year":2019,"lang":"en","type":"review","venue":"npj Digital Medicine","topic":"Genomics and Rare Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":243,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"Mohammed Bin Rashid University of Medicine and Health Sciences; Al Jalila Foundation","keywords":"Precision medicine; Autism spectrum disorder; Autism; Intellectual disability; Psychological intervention; Neuropsychology; Neurodevelopmental disorder; Intervention (counseling); Disease; Artificial intelligence; Computer science; Psychology; Medicine; Cognition; Machine learning; Neuroscience; Psychiatry; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000187447,0.0004079756,0.0009984445,0.0001879823,0.00003488177,0.00001991029,0.000379499,0.0002509027,0.00003562308],"category_scores_gemma":[0.0006616033,0.000283404,0.0002045438,0.0001849706,0.0001848615,0.00000604442,0.0001524452,0.0001392773,0.00002829379],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003570375,"about_ca_system_score_gemma":0.0002084546,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008447612,"about_ca_topic_score_gemma":0.00002275164,"domain_scores_codex":[0.9979722,0.00002746858,0.0008281266,0.0006616318,0.0001980476,0.0003124494],"domain_scores_gemma":[0.9991109,0.0001244965,0.0002208136,0.0003717056,0.00004737743,0.0001246943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004469309,0.00006037119,0.00001419747,0.001868016,0.00003472395,0.000004526286,0.00002583323,0.000002207188,0.00001820716,0.00008421006,0.001583131,0.9962599],"study_design_scores_gemma":[0.0001710339,0.0007450377,0.00002045318,0.00381082,0.0001200699,0.00002120451,0.00008266183,0.0000099323,0.000006804788,0.0007373851,0.9939516,0.0003230165],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002990461,0.9943127,0.0005991394,0.0001458382,0.0009473822,0.001372167,0.0001577407,0.000009910172,0.002156059],"genre_scores_gemma":[0.005926392,0.9894307,0.00004339654,0.0001041154,0.0006894394,0.0001132687,0.003117511,0.00006749199,0.0005076813],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9959369,"threshold_uncertainty_score":0.9999618,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0551165369490018,"score_gpt":0.3486049040711744,"score_spread":0.2934883671221726,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}