{"id":"W2989908439","doi":"10.3390/cancers11121911","title":"Immunological Effects of Epigenetic Modifiers","year":2019,"lang":"en","type":"review","venue":"Cancers","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Cancer Research; Labex Immuno-Oncology; Chancellerie des Universités de Paris; Cancéropôle Ile de France; Bristol-Myers Squibb Foundation; Institut Universitaire de France; Ligue Contre le Cancer; Fondation pour la Recherche Médicale; Institut National Du Cancer; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; E-Rare; Fondation Leducq; European Commission; Association pour la Recherche sur le Cancer; Bristol-Myers Squibb","keywords":"Epigenetics; Chromatin; DNA methylation; Histone; Methyltransferase; Cancer epigenetics; Biology; Epigenetic regulation of neurogenesis; Carcinogenesis; Acetylation; Cancer research; Chromatin remodeling; Epigenetic therapy; Histone methyltransferase; Methylation; Cancer; DNA; Genetics; Gene expression; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002832065,0.0005242079,0.0007022963,0.0009251927,0.0001761286,0.0006103381,0.0004198906,0.0006934822,0.002644945],"category_scores_gemma":[0.0003125002,0.0001669852,0.0003010672,0.0006129947,0.0003610092,0.0005528556,0.000430965,0.001041973,0.001195384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004075941,"about_ca_system_score_gemma":0.000435241,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004355899,"about_ca_topic_score_gemma":0.0007983384,"domain_scores_codex":[0.9998963,0.00002089047,0.00001132221,0.00001907482,0.00003948852,0.00001301012],"domain_scores_gemma":[0.9999026,0.00005097343,0.00001301511,0.000003990146,0.00002119873,0.000008164699],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008482805,0.00006167783,0.0002823166,0.01315316,0.00008722797,0.0002984985,0.00006671903,0.0003656208,0.01571918,0.007572935,0.01705749,0.9452503],"study_design_scores_gemma":[0.000009880154,0.0001002192,0.0008532836,0.001185485,0.00006286143,0.001553073,0.00003477237,0.00008026845,0.004428869,0.002118772,0.9895588,0.00001362981],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003424727,0.9969169,0.0002202871,0.0002102377,0.000204537,0.000004071182,0.00001640424,0.000008813727,0.002076398],"genre_scores_gemma":[0.002788926,0.9948303,0.0002378496,0.0002039247,0.0001923763,0.000008792612,0.00003310951,0.000002019173,0.001702731],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002644945,"threshold_uncertainty_score":0.00884825,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03407971042654792,"score_gpt":0.3267316316449858,"score_spread":0.2926519212184379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}