{"id":"W2989908439","doi":"10.3390/cancers11121911","title":"Immunological Effects of Epigenetic Modifiers","year":2019,"lang":"en","type":"review","venue":"Cancers","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Cancer Research; Labex Immuno-Oncology; Chancellerie des Universités de Paris; Cancéropôle Ile de France; Bristol-Myers Squibb Foundation; Institut Universitaire de France; Ligue Contre le Cancer; Fondation pour la Recherche Médicale; Institut National Du Cancer; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; E-Rare; Fondation Leducq; European Commission; Association pour la Recherche sur le Cancer; Bristol-Myers Squibb","keywords":"Epigenetics; Chromatin; DNA methylation; Histone; Methyltransferase; Cancer epigenetics; Biology; Epigenetic regulation of neurogenesis; Carcinogenesis; Acetylation; Cancer research; Chromatin remodeling; Epigenetic therapy; Histone methyltransferase; Methylation; Cancer; DNA; Genetics; Gene expression; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009193405,0.0002609528,0.0007711932,0.00006199628,0.00002244027,0.000007322225,0.0002693095,0.0004974434,0.00001233499],"category_scores_gemma":[0.00009064949,0.0002181171,0.0004014693,0.0001073299,0.00009428166,7.647325e-7,0.00009230461,0.0001367844,0.00002004129],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001480247,"about_ca_system_score_gemma":0.0006881465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001807931,"about_ca_topic_score_gemma":0.000001716805,"domain_scores_codex":[0.9988394,0.0001164339,0.0003358926,0.000387791,0.0001067433,0.0002137135],"domain_scores_gemma":[0.9990665,0.00004851231,0.0002796485,0.0005055467,0.0000473849,0.00005245561],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000007834804,0.000007680543,0.00000324256,0.009169831,0.0002185441,0.000001530992,0.000007972745,0.0001423631,0.003815715,0.00002540585,0.0001017198,0.9864982],"study_design_scores_gemma":[0.0001639494,0.0003102983,0.000006436626,0.001354771,0.0003143945,9.680223e-7,0.000002851561,0.000004700524,0.009994518,0.00002180412,0.9875686,0.0002567346],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005445488,0.9969546,0.0005104074,9.934862e-7,0.0006365456,0.0005519373,0.00002178546,0.000005425378,0.000773794],"genre_scores_gemma":[0.0008251633,0.9980388,0.0001309867,0.00001023248,0.0001405932,0.00007035117,0.0001852085,0.00003968895,0.0005589664],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9874669,"threshold_uncertainty_score":0.8894559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03407971042654792,"score_gpt":0.3267316316449858,"score_spread":0.2926519212184379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}