{"id":"W2989913242","doi":"10.1111/trf.15590","title":"Platelet vesicles are potent inflammatory mediators in red blood cell products and washing reduces the inflammatory phenotype","year":2019,"lang":"en","type":"article","venue":"Transfusion","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services; University of Alberta","funders":"Canadian Blood Services","keywords":"Platelet; Hemolysis; Chemokine; Immunology; White blood cell; Umbilical vein; Inflammation; Platelet activation; Hemoglobin; Red blood cell; CD63; Andrology; Hematocrit; Cytokine; Medicine; In vitro; Chemistry; Biochemistry; Microvesicles; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002967837,0.0001729786,0.0002752064,0.0001170466,0.00008538241,0.00001173628,0.00007817373,0.0001505816,0.00007495148],"category_scores_gemma":[0.00004051889,0.0001187235,0.00004438318,0.0001741003,0.00007831011,0.000103165,0.00002658284,0.000374643,0.00004875799],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002396311,"about_ca_system_score_gemma":0.00008150811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002130725,"about_ca_topic_score_gemma":0.00003145427,"domain_scores_codex":[0.9988043,0.0001109968,0.0002927943,0.0003513902,0.0002094528,0.0002311011],"domain_scores_gemma":[0.9994137,0.00007888545,0.00008828903,0.0002827974,0.0000544002,0.00008190699],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006288001,0.0001168691,0.03026664,0.0003803249,0.00002091903,0.00004400877,0.002925579,0.00003646727,0.9624584,0.00002862316,0.0002578358,0.002835512],"study_design_scores_gemma":[0.005716095,0.0005037204,0.4638497,0.0004120328,0.0000993872,0.00006208375,0.002203543,0.0001146512,0.5217384,0.0001000665,0.004890445,0.0003099268],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952864,0.0008588945,9.55514e-7,0.001701578,0.0004838585,0.0007146493,0.000001959475,0.00006956255,0.0008821084],"genre_scores_gemma":[0.9977835,0.001326498,0.00005957206,0.0003162563,0.0002308538,0.00001628244,0.000013093,0.00002612485,0.000227757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4407201,"threshold_uncertainty_score":0.4841402,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008282590780571097,"score_gpt":0.2023888370299617,"score_spread":0.1941062462493907,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}