{"id":"W2989913242","doi":"10.1111/trf.15590","title":"Platelet vesicles are potent inflammatory mediators in red blood cell products and washing reduces the inflammatory phenotype","year":2019,"lang":"en","type":"article","venue":"Transfusion","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services; University of Alberta","funders":"Canadian Blood Services","keywords":"Platelet; Hemolysis; Chemokine; Immunology; White blood cell; Umbilical vein; Inflammation; Platelet activation; Hemoglobin; Red blood cell; CD63; Andrology; Hematocrit; Cytokine; Medicine; In vitro; Chemistry; Biochemistry; Microvesicles; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006602479,0.0004690842,0.000471206,0.0003026665,0.0002041161,0.000800057,0.0002793707,0.0003897036,0.00180024],"category_scores_gemma":[0.0005303323,0.0001632326,0.000496896,0.0002525387,0.000289899,0.0003807643,0.0003925505,0.0004571536,0.0004635811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002835185,"about_ca_system_score_gemma":0.0002642777,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003270869,"about_ca_topic_score_gemma":0.0003430612,"domain_scores_codex":[0.9991879,0.0001960197,0.00009507893,0.0001227314,0.0002893112,0.0001089455],"domain_scores_gemma":[0.9994855,0.00009156951,0.0002525198,0.0000466333,0.0000907627,0.00003305774],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004777715,0.00008740386,0.002873054,0.0004110029,0.00007591816,0.0002590642,0.0000850763,0.0001446711,0.9837209,0.0002237357,0.0001591356,0.01148236],"study_design_scores_gemma":[0.00003484436,0.001759109,0.01786108,0.00008885895,0.0001394274,0.001350949,0.0001384457,0.0004461788,0.9713269,0.000134296,0.00670536,0.00001463489],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.953733,0.03498548,0.008511386,0.0002352618,0.0001187645,0.0001535938,0.0002907621,0.00009778464,0.001873897],"genre_scores_gemma":[0.9863319,0.005593346,0.005294065,0.000166898,0.00005977671,0.0001151501,0.0005959207,0.00003027511,0.001812721],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00180024,"threshold_uncertainty_score":0.006022394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008282590780571097,"score_gpt":0.2023888370299617,"score_spread":0.1941062462493907,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}