{"id":"W2989942076","doi":"10.1007/s10067-019-04819-4","title":"A critical review of the reproductive safety of Leflunomide","year":2019,"lang":"en","type":"review","venue":"Clinical Rheumatology","topic":"Pregnancy and Medication Impact","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; Toronto General Hospital; University of Toronto; SickKids Foundation; Mount Sinai Hospital","funders":"","keywords":"Leflunomide; Medicine; Pregnancy; Teratology; Unintended pregnancy; Pediatrics; Internal medicine; Gestation; Pharmacology; Family planning; Population; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.002561678,0.0002610256,0.005985395,0.0000666132,0.00002163039,9.058941e-7,0.0004650133,0.0006295403,0.0003674058],"category_scores_gemma":[0.09149361,0.0001438129,0.001792493,0.0003087841,0.001329917,0.00002751108,0.0002070674,0.001048771,0.0001277346],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004032915,"about_ca_system_score_gemma":0.002418878,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007106931,"about_ca_topic_score_gemma":2.937587e-7,"domain_scores_codex":[0.9941024,0.00117413,0.003637387,0.0005704761,0.0002688039,0.0002467952],"domain_scores_gemma":[0.9890788,0.006348667,0.00175311,0.002256468,0.0003899843,0.000172927],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005443872,0.0002379264,0.0003642722,0.4374409,0.0003567377,0.000003036627,0.00001550314,2.603423e-9,4.904602e-8,0.003972411,0.008158627,0.549396],"study_design_scores_gemma":[0.0002979377,0.0001317022,0.0001884355,0.4111042,0.001839019,0.0004661811,0.000003625325,1.78514e-7,6.919161e-7,0.00008269564,0.5858141,0.00007127678],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000005607871,0.9918549,0.00003244563,0.002720227,0.001525986,0.001549161,0.00005209112,0.00001497428,0.002244622],"genre_scores_gemma":[0.00004982119,0.9986358,0.0001525348,0.0006699206,0.00005736653,0.00003791554,0.00003347526,0.00002846801,0.0003346457],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5776555,"threshold_uncertainty_score":0.9161591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2018620596524767,"score_gpt":0.5171031781738302,"score_spread":0.3152411185213535,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}