{"id":"W2990026975","doi":"10.3390/molecules24234237","title":"Impact of Citral and Phloretin, Alone and in Combination, on Major Virulence Traits of Streptococcus pyogenes","year":2019,"lang":"en","type":"article","venue":"Molecules","topic":"Streptococcal Infections and Treatments","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Citral; Quorum sensing; Virulence; Biofilm; Phloretin; Streptococcus pyogenes; Microbiology; Chemistry; In silico; Biochemistry; Bacteria; Biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002909817,0.0004156776,0.0006185766,0.0003216542,0.0001592075,0.000471557,0.0002356747,0.0002788651,0.001107047],"category_scores_gemma":[0.00042047,0.0001497014,0.0004022035,0.000214813,0.0002070825,0.000264977,0.0003715276,0.0004674488,0.0001372797],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001993577,"about_ca_system_score_gemma":0.0003201136,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001133626,"about_ca_topic_score_gemma":0.001592627,"domain_scores_codex":[0.9996464,0.0001154928,0.0000266408,0.00005413406,0.0001041496,0.00005309602],"domain_scores_gemma":[0.9997948,0.00007900387,0.00002944575,0.00001600846,0.00002707899,0.00005374161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003068421,0.0009970894,0.001623918,0.0006166697,0.0001986391,0.0001960774,0.0000700762,0.001764796,0.9703683,0.00009680333,0.0003297976,0.02066937],"study_design_scores_gemma":[0.0001675981,0.01386967,0.01495615,0.00007412067,0.0005170233,0.0003947992,0.000198753,0.003703139,0.9589553,0.00008942239,0.00702797,0.00004607686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917182,0.005837033,0.0002527203,0.0001412478,0.00005280594,0.00002979103,0.0001158915,0.00001584313,0.001836516],"genre_scores_gemma":[0.9964625,0.001597377,0.0008213844,0.00006851067,0.00001543328,0.00001568746,0.00007846305,0.000006841329,0.000933841],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001133626,"threshold_uncertainty_score":0.003703415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009918795774459657,"score_gpt":0.288034556661922,"score_spread":0.2781157608874624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}