{"id":"W2990149922","doi":"10.3791/60422","title":"In Vitro Reconstitution of Spatial Cell Contact Patterns with Isolated <em>Caenorhabditis elegans</em> Embryo Blastomeres and Adhesive Polystyrene Beads","year":2019,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Multicellular organism; Blastomere; Cell biology; Caenorhabditis elegans; Cell; Cell fate determination; Biology; Embryo; Cell adhesion; In vitro; Cell type; Cell division; Genetics; Embryogenesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002424831,0.0005033186,0.0002316829,0.0002270289,0.0003064598,0.0003729122,0.00047147,0.0002991009,0.000851633],"category_scores_gemma":[0.0002022094,0.0003377461,0.0002475374,0.0001439677,0.0003365022,0.0002180187,0.0004222377,0.0007411756,0.000443816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005162149,"about_ca_system_score_gemma":0.0003392167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002403916,"about_ca_topic_score_gemma":0.004469579,"domain_scores_codex":[0.999795,0.00002492513,0.00002749743,0.00005071567,0.00006689523,0.00003500157],"domain_scores_gemma":[0.9998037,0.00003762588,0.000058108,0.0000430317,0.00001763851,0.0000398247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001430987,0.00001292479,0.0000792158,0.00001535414,0.000002959961,0.00002345908,0.00001456398,0.00008325784,0.9992487,0.0001037405,0.00001685219,0.0003845776],"study_design_scores_gemma":[0.000004892373,0.00004799369,0.001042395,0.000003460337,0.000006274543,0.00004386962,0.00001192272,0.0007362756,0.9968767,0.00001712259,0.001206348,0.000002731834],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9712669,0.0009118739,0.02417724,0.0000798927,0.00008370815,0.00009667846,0.0009385236,0.0002574844,0.002187732],"genre_scores_gemma":[0.9749365,0.0005794539,0.01933542,0.00003974517,0.000009547258,0.0001326033,0.0011887,0.00007791825,0.003700102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002403916,"threshold_uncertainty_score":0.004779816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007250324041776227,"score_gpt":0.2820060924721767,"score_spread":0.2747557684304004,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}