{"id":"W2990206078","doi":"10.1182/blood-2019-124443","title":"Clinical Impact of Ibrutinib with R-CHOP in Untreated Non-GCB DLBCL Co-Expressing BCL2 and MYC Genes in the Phase 3 Phoenix Trial","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC","funders":"","keywords":"Hazard ratio; Internal medicine; Medicine; Population; Oncology; CHOP; Diffuse large B-cell lymphoma; Ibrutinib; Vincristine; Rituximab; Cyclophosphamide; Lymphoma; Confidence interval; Leukemia; Chronic lymphocytic leukemia; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002505623,0.000948746,0.00135977,0.000196751,0.0002663067,0.001248368,0.0006623322,0.0009234186,0.002382957],"category_scores_gemma":[0.001112757,0.0002636892,0.00158501,0.0003719431,0.00055822,0.0007947497,0.0003923725,0.002187063,0.0004005284],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008806104,"about_ca_system_score_gemma":0.0007084581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007510451,"about_ca_topic_score_gemma":0.001935601,"domain_scores_codex":[0.9993068,0.0004520307,0.00002441966,0.00007883739,0.0000459004,0.00009209539],"domain_scores_gemma":[0.9994857,0.0001331574,0.0001489745,0.00004412526,0.0000290584,0.0001589904],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9132278,0.003991962,0.006567089,0.001106269,0.00244961,0.0001503227,0.000133512,0.001677573,0.006268189,0.000261782,0.00301013,0.06115574],"study_design_scores_gemma":[0.8550159,0.1153897,0.02084054,0.0002095902,0.001713229,0.0002664828,0.00008717297,0.001134563,0.001366372,0.000534756,0.003409542,0.00003205306],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9813544,0.01270591,0.0002953169,0.0008221595,0.0001690493,0.0008655784,0.0009918262,0.00007406619,0.002721808],"genre_scores_gemma":[0.9910081,0.00368725,0.0005199076,0.001023923,0.0001488883,0.0006924555,0.001898446,0.0000195284,0.001001459],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002505623,"threshold_uncertainty_score":0.01325113,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03553825901606996,"score_gpt":0.4167700193018046,"score_spread":0.3812317602857346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}