{"id":"W2990206078","doi":"10.1182/blood-2019-124443","title":"Clinical Impact of Ibrutinib with R-CHOP in Untreated Non-GCB DLBCL Co-Expressing BCL2 and MYC Genes in the Phase 3 Phoenix Trial","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC","funders":"","keywords":"Hazard ratio; Internal medicine; Medicine; Population; Oncology; CHOP; Diffuse large B-cell lymphoma; Ibrutinib; Vincristine; Rituximab; Cyclophosphamide; Lymphoma; Confidence interval; Leukemia; Chronic lymphocytic leukemia; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001145883,0.0001789477,0.0006055542,0.0001657706,0.00002339587,0.0000281282,0.0001686677,0.0001570308,0.00007706062],"category_scores_gemma":[0.000222089,0.0001005257,0.000109519,0.0003714024,0.0002112416,0.00007683047,0.00005005146,0.0003569458,0.00001540333],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005268526,"about_ca_system_score_gemma":0.0037782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001650015,"about_ca_topic_score_gemma":0.00005885695,"domain_scores_codex":[0.9980319,0.0002312272,0.0005635102,0.0003479497,0.0004313302,0.0003941302],"domain_scores_gemma":[0.9984078,0.0007616532,0.0001352066,0.0005252552,0.0000459948,0.0001240227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.1915082,0.02136793,0.7141721,0.0004838965,0.0007973139,0.001836777,0.005189599,0.00003352587,0.03906611,0.000007327511,0.0006176827,0.02491956],"study_design_scores_gemma":[0.9342444,0.005354023,0.0498867,0.0004572972,0.0001619469,0.0002851103,0.0003282578,0.002194299,0.006760939,0.000006397371,0.0001620729,0.0001585436],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968,0.0003558857,0.000002075882,0.00006038712,0.0000354907,0.001356396,0.00001348187,0.00001233819,0.001363922],"genre_scores_gemma":[0.9993843,0.00011148,0.0001107871,0.00004549013,0.0001961811,0.00002236649,0.00002195337,0.00002482343,0.00008261303],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7427362,"threshold_uncertainty_score":0.6702365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03553825901606996,"score_gpt":0.4167700193018046,"score_spread":0.3812317602857346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}