{"id":"W2990281471","doi":"10.1016/j.cellsig.2019.109486","title":"Cyclic adenosine monophosphate-dependent activation of transient receptor potential vanilloid 4 (TRPV4) channels in osteoblast-like MG-63 cells","year":2019,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université du Québec à Montréal","funders":"Canadian Institutes of Health Research; Université du Québec à Montréal; Health Research","keywords":"Forskolin; Transient receptor potential channel; Parathyroid hormone; Internal medicine; Endocrinology; Chemistry; TRPV; TRPV4; Cyclic adenosine monophosphate; Osteoblast; Cell biology; Ruthenium red; Extracellular; Calcium; Receptor; Biology; Biochemistry; TRPV1; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003496264,0.0003413376,0.0004641112,0.000302667,0.0001073798,0.00006017089,0.0004177549,0.000235791,0.0008566341],"category_scores_gemma":[0.00002701766,0.0003235754,0.0001947292,0.0005124366,0.00007102836,0.0003118593,0.00007801345,0.0003797085,0.0003184723],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001104029,"about_ca_system_score_gemma":0.00005650418,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005351352,"about_ca_topic_score_gemma":0.000001211538,"domain_scores_codex":[0.9970865,0.0001786962,0.0006979266,0.0007760124,0.000680831,0.0005800173],"domain_scores_gemma":[0.9991037,0.0001154314,0.0003149831,0.0002433423,0.00007621096,0.0001463736],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001443636,0.0002146464,0.00001343672,0.000095395,0.000008677911,0.00001213852,0.001006267,0.0912018,0.9069638,0.00003539322,0.00003629158,0.000267795],"study_design_scores_gemma":[0.001141491,0.000239922,0.000006012861,0.000122855,0.0000205105,0.000002309528,0.000353497,0.01525648,0.9818962,0.00004670776,0.0005624575,0.0003515183],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876997,0.0001522162,0.007558377,0.000132077,0.00331033,0.0008727924,0.0000164254,0.00006678172,0.0001913161],"genre_scores_gemma":[0.9975223,0.0001599398,0.0001273939,0.0001306941,0.0001933392,0.00002183613,0.00001773946,0.00007110483,0.001755687],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07594531,"threshold_uncertainty_score":0.9999216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01266958028256658,"score_gpt":0.2065947341188671,"score_spread":0.1939251538363005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}