{"id":"W2990435191","doi":"10.1101/860783","title":"RNA-Seq Analysis Reveals Localization-Associated Alternative Splicing across 13 Cell Lines","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Intron; RNA splicing; Subcellular localization; Alternative splicing; RNA; Transcriptome; Biology; Gene; RNA-binding protein; Splicing factor; RNA-Seq; Cytoplasm; Heterogeneous ribonucleoprotein particle; Exon; Computational biology; Genetics; Cell biology; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000428075,0.0003098368,0.0006216143,0.000629782,0.0004471302,0.0007989533,0.000281294,0.0003885749,0.0008983514],"category_scores_gemma":[0.0003190171,0.0001776914,0.000473524,0.0009542856,0.0002629097,0.0001172176,0.0002655681,0.0005317521,0.0005911168],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003516459,"about_ca_system_score_gemma":0.0003610811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001927318,"about_ca_topic_score_gemma":0.003712531,"domain_scores_codex":[0.9995821,0.0000248247,0.0000385011,0.0001534053,0.000141739,0.0000594647],"domain_scores_gemma":[0.9996089,0.0001559791,0.00004206092,0.00003759574,0.0001121582,0.00004326129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001834762,0.00003113723,0.006252106,0.00009696752,0.00007129334,0.0001543652,0.0001042003,0.0004236529,0.9873269,0.00014297,0.0004222209,0.004790715],"study_design_scores_gemma":[0.00005717781,0.0002435915,0.1811237,0.00002519664,0.0003016197,0.0008115627,0.0003538183,0.009781836,0.7936091,0.0003365254,0.01330322,0.00005261286],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9547924,0.001324412,0.01630745,0.0001358152,0.00005467533,0.00008192622,0.02392858,0.0004667038,0.002908272],"genre_scores_gemma":[0.8925055,0.001765303,0.03606321,0.000522156,0.00003073756,0.0002645571,0.06412815,0.0004116608,0.004308751],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001927318,"threshold_uncertainty_score":0.003832221,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01251191457050476,"score_gpt":0.2637125214425158,"score_spread":0.251200606872011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}