{"id":"W2990445893","doi":"10.1097/aln.0000000000003018","title":"Human Umbilical Cord Mesenchymal Stromal Cells Attenuate Systemic Sepsis in Part by Enhancing Peritoneal Macrophage Bacterial Killing via Heme Oxygenase-1 Induction in Rats","year":2019,"lang":"en","type":"article","venue":"Anesthesiology","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Mesenchymal stem cell; Heme oxygenase; Medicine; Stromal cell; Umbilical cord; Immunology; Sepsis; Cancer research; Pharmacology; Heme; Biology; Pathology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001162013,0.0003541261,0.001002759,0.000335498,0.00008728109,0.00002804955,0.000249419,0.0005758905,0.001182869],"category_scores_gemma":[0.00008500327,0.0003317413,0.0001248771,0.0003917094,0.0001566429,0.0001309405,0.0001124988,0.0008751718,0.0005242893],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00036937,"about_ca_system_score_gemma":0.0001552698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001216335,"about_ca_topic_score_gemma":0.0002319835,"domain_scores_codex":[0.9958768,0.0007755857,0.0009655442,0.0009099823,0.0004295111,0.001042591],"domain_scores_gemma":[0.9986892,0.0002523893,0.0001810559,0.0005184194,0.00008927382,0.0002697157],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006978551,0.0001740971,0.103149,0.0002363289,0.00001846298,0.0006474617,0.0002630899,0.00001705722,0.8938252,0.000006743573,0.0002197227,0.0007450219],"study_design_scores_gemma":[0.006011181,0.005773617,0.2467044,0.0009130429,0.00005572975,0.001797544,0.001470577,0.00126165,0.7333953,0.000042628,0.001607591,0.0009667788],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977467,0.0001894152,0.000004624455,0.0001310074,0.0005058569,0.001185342,0.000006398582,0.0000513928,0.0001792641],"genre_scores_gemma":[0.9981019,0.00004314473,0.00009959187,0.0001344148,0.0004185192,0.0000904627,0.0001049965,0.0000598768,0.0009470682],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1604299,"threshold_uncertainty_score":0.9999135,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02098264309962015,"score_gpt":0.2898002847537061,"score_spread":0.2688176416540859,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}