{"id":"W2990457166","doi":"10.1002/jcph.1543","title":"Abuse Potential of Lasmiditan: A Phase 1 Randomized, Placebo‐ and Alprazolam‐Controlled Crossover Study","year":2019,"lang":"en","type":"article","venue":"The Journal of Clinical Pharmacology","topic":"Migraine and Headache Studies","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"De Beers (Canada)","funders":"Eli Lilly and Company","keywords":"Alprazolam; Placebo; Medicine; Adverse effect; Tolerability; Anesthesia; Internal medicine; Psychiatry; Anxiety","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00343047,0.002071237,0.003616733,0.0007783882,0.0007622103,0.001013648,0.001187584,0.001919454,0.007212672],"category_scores_gemma":[0.003051963,0.001120108,0.001717338,0.0006454884,0.001639513,0.001510588,0.000369336,0.002371508,0.00112555],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008674245,"about_ca_system_score_gemma":0.001903843,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007771719,"about_ca_topic_score_gemma":0.001709406,"domain_scores_codex":[0.998252,0.0009927023,0.0001157219,0.0002726604,0.0001696741,0.000197303],"domain_scores_gemma":[0.997812,0.0006210207,0.0005524203,0.0002557262,0.0002490471,0.0005097641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9294151,0.04532802,0.0007725583,0.000499243,0.0006156714,0.00006515098,0.0001078111,0.0002413636,0.01029119,0.0001221506,0.0005622583,0.01197947],"study_design_scores_gemma":[0.7786254,0.2174607,0.00187014,0.00001903554,0.0003167257,0.00003940657,0.00002659868,0.0003283884,0.000746912,0.00008925927,0.0004578906,0.00001958135],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850152,0.001354206,0.001423096,0.0003108695,0.0002765376,0.009523173,0.0009457754,0.0001479958,0.001003155],"genre_scores_gemma":[0.9743172,0.002014787,0.004102937,0.0008709846,0.0006325772,0.0137218,0.001065272,0.00004504906,0.003229345],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007212672,"threshold_uncertainty_score":0.02412879,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03858354255254871,"score_gpt":0.4594060173581783,"score_spread":0.4208224748056296,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}