{"id":"W2990558225","doi":"10.1016/j.niox.2019.11.005","title":"Nitric oxide signaling inhibits microglia proliferation by activation of protein kinase-G","year":2019,"lang":"en","type":"article","venue":"Nitric Oxide","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Microglia; Cell biology; Nitric oxide synthase; Nitric oxide; Biology; Signal transduction; Cell cycle; Kinase; Protein kinase A; Cell growth; Cell; Chemistry; Endocrinology; Molecular biology; Immunology; Inflammation; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002729699,0.000239504,0.0002505374,0.0003824472,0.0001425992,0.00008763613,0.0002304519,0.0001171015,0.0001467504],"category_scores_gemma":[0.0006090906,0.0002409045,0.00008502939,0.001017139,0.00003093703,0.0005619347,0.00005333335,0.0002512228,0.0003078725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006007846,"about_ca_system_score_gemma":0.00009229875,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008268888,"about_ca_topic_score_gemma":4.153409e-7,"domain_scores_codex":[0.9976211,0.0002942447,0.0006020594,0.0005680688,0.0006163364,0.0002982028],"domain_scores_gemma":[0.9987896,0.0001741086,0.0004465199,0.0003464464,0.0001443038,0.00009901889],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006134921,0.0000942432,0.0001566168,0.0000521578,0.000002148047,0.000002335945,0.00002386168,0.000250516,0.9967952,0.00188573,0.0002681043,0.0004077303],"study_design_scores_gemma":[0.0007454279,0.00006624547,0.0001820097,0.00003957402,0.000007735992,0.000008251208,0.00001646327,0.001674137,0.9959918,0.0003305206,0.0007115372,0.0002263036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953833,0.00001478613,0.002277035,0.0001621492,0.00006923373,0.001389879,0.00001827228,0.000167643,0.0005176727],"genre_scores_gemma":[0.9952573,0.000008442897,0.0008082514,0.0008093177,0.00004823185,0.00007244252,0.0000208641,0.00004372551,0.002931451],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002413779,"threshold_uncertainty_score":0.98238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01737915960959534,"score_gpt":0.2279522106779702,"score_spread":0.2105730510683748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}