{"id":"W2990623561","doi":"10.1182/bloodadvances.2019000176","title":"Human ectoenzyme-expressing ILC3: immunosuppressive innate cells that are depleted in graft-versus-host disease","year":2019,"lang":"en","type":"article","venue":"Blood Advances","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek; ZonMw; Amsterdam University Medical Centers","keywords":"Innate lymphoid cell; Immunology; Innate immune system; Disease; Graft-versus-host disease; Host (biology); Biology; Medicine; Immune system; Genetics; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001012239,0.0002411654,0.0002287452,0.0001885595,0.0002052982,0.0003497342,0.0001644328,0.000293963,0.001516853],"category_scores_gemma":[0.0001471142,0.00008096093,0.0002567361,0.0003258745,0.0001281886,0.0001447035,0.0001818878,0.000425969,0.0005851503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002059145,"about_ca_system_score_gemma":0.0001908956,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007024397,"about_ca_topic_score_gemma":0.000845413,"domain_scores_codex":[0.9998595,0.00001133437,0.00001313929,0.00003488266,0.00003667212,0.00004454201],"domain_scores_gemma":[0.9999214,0.00001102616,0.00001493115,0.00001510467,0.00001370057,0.00002385881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003170083,0.0000485067,0.002101397,0.00002806054,0.000008572931,0.0004376182,0.00003727532,0.00004658215,0.992335,0.00008115399,0.0002131844,0.00434563],"study_design_scores_gemma":[0.000129406,0.001237109,0.06527687,0.0000229301,0.000113075,0.01762285,0.0001821321,0.001629209,0.8846767,0.0001867832,0.02889556,0.00002744395],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942731,0.001521859,0.001701265,0.00007997089,0.00002587349,0.00008397159,0.0006641417,0.00005642125,0.001593365],"genre_scores_gemma":[0.9935628,0.0006643492,0.001723584,0.0001303192,0.00001976592,0.00008894465,0.002016397,0.00002728738,0.001766451],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001516853,"threshold_uncertainty_score":0.005074382,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01323746299447102,"score_gpt":0.2386078850368114,"score_spread":0.2253704220423404,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}