{"id":"W2990623561","doi":"10.1182/bloodadvances.2019000176","title":"Human ectoenzyme-expressing ILC3: immunosuppressive innate cells that are depleted in graft-versus-host disease","year":2019,"lang":"en","type":"article","venue":"Blood Advances","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek; ZonMw; Amsterdam University Medical Centers","keywords":"Innate lymphoid cell; Immunology; Innate immune system; Disease; Graft-versus-host disease; Host (biology); Biology; Medicine; Immune system; Genetics; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001217546,0.0003864595,0.0005031624,0.0001937567,0.000309976,0.00004711688,0.0004685857,0.0002205655,0.0002662006],"category_scores_gemma":[0.0000740997,0.0003512232,0.0001377224,0.0002310333,0.0002375433,0.0005777591,0.0001908476,0.0004678191,0.0005079038],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003501091,"about_ca_system_score_gemma":0.00007637058,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005708,"about_ca_topic_score_gemma":0.0001262733,"domain_scores_codex":[0.9979318,0.0002409887,0.0003737986,0.0006415115,0.00008721077,0.0007247354],"domain_scores_gemma":[0.9988152,0.0001479468,0.0003286673,0.000571371,0.00007649418,0.00006036381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006153107,0.0004415897,0.04019961,0.0001593637,0.0001689891,0.0001018956,0.0007026027,0.00007201836,0.95649,0.0002223137,0.000547711,0.000278581],"study_design_scores_gemma":[0.01067099,0.0003682574,0.06845303,0.0006171755,0.0001680431,0.00001412188,0.00152622,0.000004970264,0.8324743,0.0002943834,0.08449487,0.0009136538],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802881,0.01366447,0.000005259526,0.00004190632,0.001886338,0.0004517618,0.001072665,0.0001448873,0.002444636],"genre_scores_gemma":[0.9976715,0.0003985042,0.00005313734,0.0001305646,0.00006476954,0.00004812198,0.0002092541,0.00004378632,0.00138031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1240157,"threshold_uncertainty_score":0.999894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01323746299447102,"score_gpt":0.2386078850368114,"score_spread":0.2253704220423404,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}