{"id":"W2990732386","doi":"10.1182/blood-2019-129323","title":"Minimal Residual Disease (MRD) Assessment in the ECOG1411 Randomized Phase 2 Trial of Front-Line Bendamustine-Rituximab (BR)-Based Induction Followed By Rituximab (R) ± Lenalidomide (L) Consolidation for Mantle Cell Lymphoma (MCL)","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Bendamustine; Medicine; Mantle cell lymphoma; Minimal residual disease; Rituximab; Lenalidomide; Internal medicine; Oncology; Bortezomib; Progression-free survival; Multiple myeloma; Surgery; Lymphoma; Chemotherapy; Leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00377741,0.002725892,0.002230722,0.000511428,0.0005093565,0.001143161,0.00103921,0.001876225,0.005239545],"category_scores_gemma":[0.001387389,0.0008999191,0.00128108,0.0005322073,0.001362962,0.0008917,0.0007416005,0.002477037,0.001128311],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001917774,"about_ca_system_score_gemma":0.002214698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001458483,"about_ca_topic_score_gemma":0.005416494,"domain_scores_codex":[0.9982377,0.001049344,0.00007734333,0.0002734205,0.0001223224,0.0002398361],"domain_scores_gemma":[0.9992505,0.0001243284,0.0001482056,0.00009352675,0.00005473795,0.0003286191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9629651,0.009104831,0.005937979,0.000138867,0.0004192897,0.00004875631,0.00004874613,0.0005439852,0.003700931,0.0001739185,0.001633451,0.01528406],"study_design_scores_gemma":[0.8064812,0.1709311,0.01619936,0.00002689695,0.0004443327,0.00008679618,0.00002999224,0.0007211721,0.00146994,0.0003585959,0.003221591,0.00002884056],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825385,0.001287541,0.0006463963,0.000491743,0.0002126434,0.009209277,0.002680287,0.00008132333,0.002852463],"genre_scores_gemma":[0.9747329,0.0006494269,0.002184497,0.001479298,0.0002092849,0.008465371,0.005304926,0.00006210633,0.006912224],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005239545,"threshold_uncertainty_score":0.01997709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01677914972012946,"score_gpt":0.299942393250783,"score_spread":0.2831632435306535,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}