{"id":"W2990742514","doi":"10.3390/molecules24234239","title":"Experimental Cannabinoid 2 Receptor Activation by Phyto-Derived and Synthetic Cannabinoid Ligands in LPS-Induced Interstitial Cystitis in Mice","year":2019,"lang":"en","type":"article","venue":"Molecules","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Cannabinoid; Cannabinoid receptor; Chemistry; Endocannabinoid system; Interstitial cystitis; Cannabinoid receptor antagonist; Cannabinoid receptor type 2; Cannabinoid Receptor Agonists; Pharmacology; Synthetic cannabinoids; Receptor; Stereochemistry; Biochemistry; Medicine; Internal medicine; Antagonist; Urinary system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001865425,0.0002718459,0.0004218453,0.0003550094,0.00004702589,0.00005767361,0.0001312092,0.0001801813,0.0002782193],"category_scores_gemma":[0.00009892001,0.000270023,0.00007156435,0.0003410592,0.0001105705,0.0001545101,0.0001081846,0.0003933371,0.0000359504],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004849097,"about_ca_system_score_gemma":0.00021963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003574075,"about_ca_topic_score_gemma":0.0002794618,"domain_scores_codex":[0.9980818,0.00007435347,0.0003636259,0.0005761543,0.0003861469,0.0005179027],"domain_scores_gemma":[0.9993777,0.00001172731,0.00007349312,0.0002559994,0.00007564014,0.0002054493],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005361782,0.0002602737,0.002395959,0.0001084993,0.00001562505,0.00003564869,0.001094747,0.000004314529,0.9841136,0.00003721111,0.009776544,0.00162135],"study_design_scores_gemma":[0.003145919,0.000755719,0.01435122,0.000326748,0.000008473323,0.00002949622,0.001566623,0.0002539558,0.9751411,0.000008537352,0.004118428,0.0002937949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914433,0.0005569188,0.00001270075,0.005658026,0.0001964149,0.0008631593,0.00002461551,0.00003597444,0.001208863],"genre_scores_gemma":[0.9963151,0.00003928488,0.00004054953,0.0004300611,0.00007151854,0.0001915067,0.00007059686,0.00005060727,0.002790733],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01195526,"threshold_uncertainty_score":0.9999752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00811744516639319,"score_gpt":0.261672659231618,"score_spread":0.2535552140652249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}