{"id":"W2990774494","doi":"10.1093/jncics/pkz096","title":"Randomized Phase II Trial of Exercise, Metformin, or Both on Metabolic Biomarkers in Colorectal and Breast Cancer Survivors","year":2019,"lang":"en","type":"article","venue":"JNCI Cancer Spectrum","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Center for Advancing Translational Sciences; National Cancer Institute; George W. Stone Family Foundation; Memorial Sloan-Kettering Cancer Center; Susan G. Komen for the Cure","keywords":"Medicine; Metformin; Internal medicine; Breast cancer; Insulin resistance; Colorectal cancer; Randomized controlled trial; Anthropometry; Homeostatic model assessment; Insulin; Oncology; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001743204,0.002103609,0.003345709,0.0006336512,0.0005407399,0.001097762,0.0009242702,0.001960848,0.009833802],"category_scores_gemma":[0.002138805,0.0008221415,0.001827034,0.000569837,0.001037777,0.0009425562,0.0007063464,0.00312556,0.001318623],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007624163,"about_ca_system_score_gemma":0.001567825,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001217252,"about_ca_topic_score_gemma":0.00250924,"domain_scores_codex":[0.9991522,0.0004616403,0.00004503711,0.0001569553,0.00006067831,0.0001235243],"domain_scores_gemma":[0.9986646,0.0002965106,0.000333552,0.0001292222,0.0001050718,0.0004709746],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9819871,0.008816277,0.000423307,0.0002840666,0.0005363847,0.00001755386,0.00002456384,0.0001423049,0.0009138889,0.00005334135,0.000621517,0.006179779],"study_design_scores_gemma":[0.964905,0.03380237,0.0006604497,0.0000143523,0.0001695037,0.000007995637,0.000009520044,0.00009348121,0.00008066788,0.0000474421,0.0002049908,0.000004241186],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.976343,0.003549926,0.0009170615,0.001313999,0.001141389,0.01214047,0.001931242,0.0001746383,0.002488235],"genre_scores_gemma":[0.9522355,0.003199495,0.00298889,0.003178702,0.001007607,0.02819049,0.002623316,0.00004331738,0.006532757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009833802,"threshold_uncertainty_score":0.03289735,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008891338258040034,"score_gpt":0.2807000271834709,"score_spread":0.2718086889254309,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}