{"id":"W2990777397","doi":"10.1148/rycan.2019190035","title":"Development of a Human Photoacoustic Imaging Reporter Gene Using the Clinical Dye Indocyanine Green","year":2019,"lang":"en","type":"article","venue":"Radiology Imaging Cancer","topic":"Photoacoustic and Ultrasonic Imaging","field":"Engineering","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute","funders":"","keywords":"Indocyanine green; In vivo; Reporter gene; Medicine; In vitro; Fluorescence; Gene; Molecular biology; Gene expression; Cancer research; Pathology; Biology; Biochemistry; Genetics; Optics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008115162,0.0002885756,0.0005399579,0.0001247919,0.000149345,0.00002255704,0.0003488607,0.00006778001,0.0002276897],"category_scores_gemma":[0.00003377379,0.0002337591,0.0001275581,0.0001889315,0.000249805,0.0001340635,0.00008552227,0.0004242857,0.000009177036],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002746056,"about_ca_system_score_gemma":0.0002341267,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001828387,"about_ca_topic_score_gemma":0.00001754672,"domain_scores_codex":[0.9977924,0.0000729653,0.000958926,0.0004014666,0.0001943109,0.0005799955],"domain_scores_gemma":[0.9989366,0.0001572479,0.0002330342,0.0005022433,0.00008663245,0.00008424526],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.00001742878,0.00002917368,0.2412311,0.0001447277,0.0003145693,0.00005082941,0.001383053,0.009044778,0.7342043,0.00001444007,0.0009217088,0.01264394],"study_design_scores_gemma":[0.002854138,0.00002578886,0.05972927,0.0004400718,0.0005077436,0.001603449,0.001015457,0.8723668,0.05344176,0.0001722618,0.006580761,0.001262434],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9733719,0.001804542,0.02190384,0.0000812662,0.00146136,0.0003503351,0.00001358387,0.0001748745,0.0008382518],"genre_scores_gemma":[0.9937963,0.00004207169,0.005265323,0.0003701288,0.0003048825,0.00003433292,0.00001155369,0.00007108963,0.0001043299],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8633221,"threshold_uncertainty_score":0.9532421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02536317097062998,"score_gpt":0.313813402132452,"score_spread":0.288450231161822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}