{"id":"W2990777397","doi":"10.1148/rycan.2019190035","title":"Development of a Human Photoacoustic Imaging Reporter Gene Using the Clinical Dye Indocyanine Green","year":2019,"lang":"en","type":"article","venue":"Radiology Imaging Cancer","topic":"Photoacoustic and Ultrasonic Imaging","field":"Engineering","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute","funders":"","keywords":"Indocyanine green; In vivo; Reporter gene; Medicine; In vitro; Fluorescence; Gene; Molecular biology; Gene expression; Cancer research; Pathology; Biology; Biochemistry; Genetics; Optics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005666005,0.0003753901,0.0003866395,0.0002443772,0.0001341166,0.0004010488,0.0004199188,0.000637214,0.001464668],"category_scores_gemma":[0.0003438889,0.0001849718,0.0004816185,0.0002690186,0.0004918969,0.0003183168,0.0002218572,0.0008433979,0.000590133],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006793979,"about_ca_system_score_gemma":0.0007618662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001019701,"about_ca_topic_score_gemma":0.0006256317,"domain_scores_codex":[0.9995839,0.0000472817,0.000023723,0.0001113133,0.000163692,0.00007011012],"domain_scores_gemma":[0.9998088,0.00003366231,0.00005758576,0.00002160985,0.00004143935,0.00003680585],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006982691,0.00003488542,0.0001364974,0.00005343119,0.00000418225,0.00002924408,0.00002049301,0.0001210311,0.9967243,0.000385302,0.000147605,0.002273174],"study_design_scores_gemma":[0.00003404469,0.0004904154,0.0009246654,0.00001203303,0.00001671994,0.0003014961,0.00002231243,0.001560815,0.9882627,0.00007627995,0.008290292,0.000008260271],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7385451,0.005202412,0.2436299,0.002516042,0.0003863782,0.001061159,0.00205848,0.001543608,0.005056918],"genre_scores_gemma":[0.8971965,0.002699132,0.08939682,0.000504604,0.00005731044,0.0006444505,0.001967635,0.00016476,0.00736882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001464668,"threshold_uncertainty_score":0.004929423,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02536317097062998,"score_gpt":0.313813402132452,"score_spread":0.288450231161822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}