{"id":"W2990854490","doi":"10.1016/s2352-3018(19)30341-8","title":"On-demand pre-exposure prophylaxis with tenofovir disoproxil fumarate plus emtricitabine among men who have sex with men with less frequent sexual intercourse: a post-hoc analysis of the ANRS IPERGAY trial","year":2019,"lang":"en","type":"article","venue":"The Lancet HIV","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Agence Nationale de Recherches sur le Sida et les Hépatites Virales; Fondation Pierre Fabre; Canadian HIV Trials Network, Canadian Institutes of Health Research; Sidaction; Styrelsen för Internationellt Utvecklingssamarbete; Gilead Sciences; CHIST-ERA; Bill and Melinda Gates Foundation","keywords":"Emtricitabine; Medicine; Pre-exposure prophylaxis; Pill; Men who have sex with men; Population; Placebo; Gynecology; Incidence (geometry); Obstetrics; Internal medicine; Human immunodeficiency virus (HIV); Viral load; Immunology; Antiretroviral therapy; Environmental health; Pharmacology; Syphilis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007640991,0.000348391,0.001113875,0.000282044,0.0001670185,0.00007488704,0.0005914974,0.0000944158,0.0002676055],"category_scores_gemma":[0.00007238929,0.0001387621,0.0001842325,0.001016285,0.0005111881,0.0001654275,0.0001271401,0.0006683217,0.00001618904],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001848685,"about_ca_system_score_gemma":0.0003397322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007625274,"about_ca_topic_score_gemma":0.002157123,"domain_scores_codex":[0.9970312,0.0003894234,0.0004298632,0.0005155857,0.001054184,0.0005797481],"domain_scores_gemma":[0.9976524,0.0001473146,0.0003151157,0.001376316,0.0003342866,0.0001745293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.3780862,0.002147108,0.5300813,0.0009785667,0.02011747,0.0001490094,0.02149999,0.004714228,0.004136407,0.0004653044,0.03135749,0.006266862],"study_design_scores_gemma":[0.1775421,0.2499488,0.4525044,0.002867982,0.007442574,0.0001003581,0.03080919,0.07334275,0.003322028,0.00007223411,0.0006602861,0.001387347],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9752287,0.0001336137,0.0003211384,0.002129089,0.00001171846,0.002764588,0.0002397886,0.00004102978,0.01913036],"genre_scores_gemma":[0.877131,0.00001618414,0.00003980627,0.00008207886,0.0001613327,0.0001959189,0.00008342874,0.00004551304,0.1222447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2478016,"threshold_uncertainty_score":0.5658556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01385446091486169,"score_gpt":0.2790109902988977,"score_spread":0.265156529384036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}