{"id":"W2990854490","doi":"10.1016/s2352-3018(19)30341-8","title":"On-demand pre-exposure prophylaxis with tenofovir disoproxil fumarate plus emtricitabine among men who have sex with men with less frequent sexual intercourse: a post-hoc analysis of the ANRS IPERGAY trial","year":2019,"lang":"en","type":"article","venue":"The Lancet HIV","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Agence Nationale de Recherches sur le Sida et les Hépatites Virales; Fondation Pierre Fabre; Canadian HIV Trials Network, Canadian Institutes of Health Research; Sidaction; Styrelsen för Internationellt Utvecklingssamarbete; Gilead Sciences; CHIST-ERA; Bill and Melinda Gates Foundation","keywords":"Emtricitabine; Medicine; Pre-exposure prophylaxis; Pill; Men who have sex with men; Population; Placebo; Gynecology; Incidence (geometry); Obstetrics; Internal medicine; Human immunodeficiency virus (HIV); Viral load; Immunology; Antiretroviral therapy; Environmental health; Pharmacology; Syphilis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001932955,0.001674412,0.003681416,0.0002234775,0.0002551993,0.001010697,0.0009149475,0.001035846,0.005929085],"category_scores_gemma":[0.002664657,0.0005396715,0.00451506,0.000259139,0.0006164479,0.0009513239,0.0004989846,0.003179505,0.0005522686],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007719583,"about_ca_system_score_gemma":0.000889292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002310447,"about_ca_topic_score_gemma":0.005487578,"domain_scores_codex":[0.9985317,0.0009535894,0.00006747889,0.0001827478,0.00006746268,0.0001969435],"domain_scores_gemma":[0.9985843,0.0007272208,0.0002345797,0.0001504278,0.00007643876,0.0002270777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9788496,0.0007431717,0.001331373,0.000664117,0.006687812,0.00003771887,0.0000376842,0.0004871696,0.0009931558,0.0001106346,0.0004724434,0.009585153],"study_design_scores_gemma":[0.8454994,0.1020632,0.02567397,0.0002316981,0.02026311,0.0001330374,0.000177677,0.002180317,0.001398965,0.0006013637,0.00170087,0.00007630818],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883212,0.006366957,0.0003936723,0.0005469269,0.0005635756,0.000423157,0.0009785891,0.00005837832,0.002347647],"genre_scores_gemma":[0.9956032,0.001446562,0.0002951402,0.000249131,0.000239517,0.0001574408,0.0005214035,0.00001470524,0.001472864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005929085,"threshold_uncertainty_score":0.01983476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01385446091486169,"score_gpt":0.2790109902988977,"score_spread":0.265156529384036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}