{"id":"W2990885696","doi":"10.1016/j.cgh.2019.11.030","title":"Association Between Levels of Sex Hormones and Risk of Esophageal Adenocarcinoma and Barrett’s Esophagus","year":2019,"lang":"en","type":"article","venue":"Clinical Gastroenterology and Hepatology","topic":"Esophageal Cancer Research and Treatment","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"Ruth och Richard Julins Stiftelse; Bengt Ihres Foundation; Queen's University; Cancerfonden; Queen's University Belfast; National Institute for Health and Care Research; National Natural Science Foundation of China; National Cancer Institute; Vetenskapsrådet; Cancer Research UK","keywords":"Mendelian randomization; Medicine; Internal medicine; Hormone; Odds ratio; Sex hormone-binding globulin; Testosterone (patch); Dehydroepiandrosterone sulfate; Oncology; Endocrinology; Luteinizing hormone; Physiology; Gastroenterology; Androgen; Genotype; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004751044,0.0002844775,0.0003148723,0.0006159983,0.0002407223,0.0005268797,0.0002199991,0.0005235883,0.002230186],"category_scores_gemma":[0.002508678,0.0002937518,0.0009298642,0.0008272783,0.0002728668,0.000350379,0.0002735333,0.0008222849,0.0001610042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002199194,"about_ca_system_score_gemma":0.0002344316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003650996,"about_ca_topic_score_gemma":0.003759982,"domain_scores_codex":[0.9996359,0.0001165291,0.00004458759,0.0000676132,0.00006952051,0.00006586321],"domain_scores_gemma":[0.9976342,0.0008380751,0.0007709202,0.0002070142,0.0001793923,0.0003705469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005551507,0.0000275374,0.9970036,0.000014176,0.0003063498,0.00008647821,0.00001772962,0.00004605441,0.0005754343,0.00002556127,0.00004720635,0.001294794],"study_design_scores_gemma":[0.000006498848,0.0000993069,0.9991137,0.00000348158,0.00008457972,0.0002253799,0.00003533202,0.000151535,0.00008068122,0.00002526159,0.000170571,0.000003642132],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931974,0.003772328,0.0002078562,0.000143875,0.00005374325,0.000006348813,0.0005838868,0.00001333507,0.002021208],"genre_scores_gemma":[0.9988531,0.0003814971,0.0001292603,0.0000278912,0.00003241004,0.000002533252,0.0002113434,0.000003020909,0.0003589445],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003650996,"threshold_uncertainty_score":0.007460773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03217063649165545,"score_gpt":0.3364274214705327,"score_spread":0.3042567849788773,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}