{"id":"W2990918333","doi":"10.1038/s41598-019-54493-4","title":"Impact of Q-Griffithsin anti-HIV microbicide gel in non-human primates: In situ analyses of epithelial and immune cell markers in rectal mucosa","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Public Health Agency of Canada","funders":"National Institute of Allergy and Infectious Diseases; Centers for Disease Control and Prevention; National Institutes of Health; Vetenskapsrådet; Karolinska Institutet","keywords":"Microbicide; Lamina propria; Ex vivo; In vivo; Biology; Immune system; Immunology; Epithelium; Pathology; Medicine; Human immunodeficiency virus (HIV)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000344462,0.0003612514,0.0003221434,0.0001892883,0.0001410093,0.0002389592,0.0001616988,0.0003293144,0.001985215],"category_scores_gemma":[0.0001673298,0.0001754194,0.000252797,0.0001166501,0.0003567369,0.0001298259,0.000124001,0.0004833245,0.0003598498],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001756729,"about_ca_system_score_gemma":0.0002227268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001910386,"about_ca_topic_score_gemma":0.003500665,"domain_scores_codex":[0.9997814,0.00007771623,0.00000758538,0.00004873771,0.00004335392,0.000041111],"domain_scores_gemma":[0.9998715,0.00003385311,0.00003011673,0.0000171113,0.00002351787,0.00002392151],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002127191,0.00003708407,0.0001235264,0.00003576401,0.000003445095,0.00002336566,0.00002517277,0.00002150765,0.998659,0.00001015179,0.00001092827,0.0008372213],"study_design_scores_gemma":[0.00002521693,0.005955079,0.01668052,0.00001211005,0.00003781958,0.0001825096,0.0001788676,0.0007879584,0.9741842,0.00004121113,0.001906564,0.000007966871],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932284,0.00158562,0.003190936,0.00008730453,0.00003016168,0.0001064343,0.0002834289,0.00006847809,0.001419274],"genre_scores_gemma":[0.9869964,0.001097706,0.006504851,0.0001105801,0.00001846627,0.0001592824,0.0002902045,0.00004080736,0.00478167],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001985215,"threshold_uncertainty_score":0.006641209,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01140703434225842,"score_gpt":0.3050403186718533,"score_spread":0.2936332843295948,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}