{"id":"W2991171257","doi":"10.3390/cancers11111817","title":"Biological Functions of the ING Proteins","year":2019,"lang":"en","type":"review","venue":"Cancers","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Biology; Gene knockout; Signal transducing adaptor protein; Cell biology; Epigenetics; Chromatin; Knockout mouse; H3K4me3; Histone; Histone deacetylase; Genetics; Gene; Signal transduction; Gene expression; Promoter","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000203833,0.0007680338,0.0006626974,0.001329773,0.0002344618,0.0006882564,0.0005373148,0.0006127374,0.003086735],"category_scores_gemma":[0.0002358905,0.000157899,0.0003148747,0.0009871837,0.0003955691,0.0006592743,0.0005158416,0.001134845,0.002124176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000526652,"about_ca_system_score_gemma":0.0006048898,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000679895,"about_ca_topic_score_gemma":0.0007589589,"domain_scores_codex":[0.9998931,0.00001285411,0.0000149636,0.00002373471,0.00003907072,0.00001625371],"domain_scores_gemma":[0.9999413,0.00002328058,0.000009161736,0.000003219116,0.00001525558,0.000007748341],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007124006,0.00004453062,0.0002253595,0.00900713,0.00005365331,0.0003096121,0.00007066012,0.0004095577,0.01137856,0.007509364,0.02511358,0.9458067],"study_design_scores_gemma":[0.000004649401,0.00003390358,0.00063526,0.0007559221,0.0000269786,0.001350236,0.00002565899,0.00003731596,0.001838371,0.001365692,0.9939173,0.000008593333],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003016974,0.9957717,0.0002282099,0.0002067334,0.0001838206,0.000003631143,0.00003918397,0.00001183163,0.003253186],"genre_scores_gemma":[0.001870387,0.9945554,0.0002715903,0.0001829511,0.0001399432,0.000008450147,0.00009228225,0.00000321387,0.002875883],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003086735,"threshold_uncertainty_score":0.01032621,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07523882210073754,"score_gpt":0.3327366952855061,"score_spread":0.2574978731847686,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}