{"id":"W2991226328","doi":"10.1016/j.peptides.2019.170206","title":"Cellular mechanisms governing glucose-dependent insulinotropic polypeptide secretion","year":2019,"lang":"en","type":"review","venue":"Peptides","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Medical Research Council Canada; Wellcome Trust","keywords":"Incretin; Nutrient sensing; Enteroendocrine cell; Internal medicine; Endocrinology; Glucose homeostasis; Receptor; Biology; Secretion; Postprandial; Carbohydrate metabolism; Biochemistry; Chemistry; Insulin; Hormone; Signal transduction; Endocrine system; Type 2 diabetes; Insulin resistance; Diabetes mellitus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002212035,0.0006731206,0.002016537,0.0002708784,0.00008003148,0.00008175011,0.0002404928,0.0003213429,0.000441039],"category_scores_gemma":[0.00004946722,0.0005307702,0.0007949932,0.0002205334,0.00003316146,0.0001093915,0.0002257981,0.0004143603,0.005502881],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005555264,"about_ca_system_score_gemma":0.000180422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004626961,"about_ca_topic_score_gemma":0.000005853521,"domain_scores_codex":[0.9973835,0.0000963874,0.0006488261,0.0007230437,0.0006131057,0.0005350843],"domain_scores_gemma":[0.998432,0.00008830682,0.0004519539,0.0007894597,0.00005397118,0.0001843494],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001425671,0.0001965058,0.00002544889,0.02688199,0.001130666,0.0001557896,0.00003762323,7.70117e-7,0.00009700409,0.00235282,0.0008725623,0.9682345],"study_design_scores_gemma":[0.0007305975,0.0003787905,0.00001564961,0.0122674,0.005758503,0.00001337663,0.00003765067,0.00001655732,0.0001082923,0.0001098761,0.9801063,0.0004570004],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000116212,0.9836357,0.0007885423,0.00003225191,0.0007536234,0.002044181,0.00004519826,0.0002423777,0.01234187],"genre_scores_gemma":[0.0002774493,0.971517,0.00174796,0.0001301161,0.0003931377,0.0001936696,0.001145137,0.000158883,0.0244367],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9792337,"threshold_uncertainty_score":0.9997144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04152330135232617,"score_gpt":0.2936700283790004,"score_spread":0.2521467270266742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}