{"id":"W2991332674","doi":"10.1038/s41409-019-0747-2","title":"Evaluating the clinical effectiveness of autologous haematopoietic stem cell transplantation versus disease-modifying therapy in multiple sclerosis using a matching-adjusted indirect comparison: an exploratory study from the Autoimmune Diseases Working Party (ADWP) of the European Society of Bone and Marrow Transplantation (EBMT)","year":2019,"lang":"en","type":"letter","venue":"Bone Marrow Transplantation","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Medicine; Multiple sclerosis; Transplantation; Oncology; Stem cell; Autoimmune disease; Matching (statistics); Disease; Hematopoietic stem cell transplantation; Immunology; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.004939376,0.0006379727,0.00181176,0.0001902228,0.0004370776,0.00006153226,0.00042386,0.0003137987,0.000005708054],"category_scores_gemma":[0.00009049508,0.0004064373,0.0005939059,0.0005806636,0.0006477814,0.0002446859,0.00005989648,0.00144539,7.305098e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001356232,"about_ca_system_score_gemma":0.0003338049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008304984,"about_ca_topic_score_gemma":0.0004321539,"domain_scores_codex":[0.9842182,0.01076768,0.002068135,0.0008874022,0.001575488,0.0004831319],"domain_scores_gemma":[0.9890174,0.008301787,0.001496208,0.0008414628,0.0002613654,0.00008176798],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02712785,0.001592436,0.7347393,0.0154832,0.001356076,0.0001191518,0.0758556,0.006745551,0.1265375,8.722998e-7,0.00008850147,0.01035395],"study_design_scores_gemma":[0.0166198,0.0008690916,0.9544483,0.007161661,0.002985191,0.00000916853,0.004558064,0.009969072,0.002991157,0.000008792365,0.000003211012,0.0003764636],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889456,0.002846353,0.0004966334,0.001162656,0.0003854926,0.005225774,0.0008725956,0.00005647387,0.000008395238],"genre_scores_gemma":[0.9933152,0.004383921,0.0003005319,0.000506577,0.0001826037,0.0002031993,0.0009890575,0.0001160808,0.000002811969],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.219709,"threshold_uncertainty_score":0.9998388,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2636855929662756,"score_gpt":0.3761678318912449,"score_spread":0.1124822389249693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}