{"id":"W2991533290","doi":"10.1515/hsz-2019-0341","title":"Aha-type co-chaperones: the alpha or the omega of the Hsp90 ATPase cycle?","year":2019,"lang":"en","type":"review","venue":"Biological Chemistry","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"The King's University; University of Alberta","funders":"","keywords":"Hsp90; Chaperone (clinical); Heat shock protein; ATPase; Cell biology; Chemistry; Context (archaeology); Biochemistry; Biology; Enzyme; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002809287,0.0006427428,0.0009605424,0.001688234,0.0002259905,0.000898771,0.0006528368,0.0007059291,0.003656881],"category_scores_gemma":[0.0003297884,0.0001935403,0.0002631327,0.002224671,0.0002883067,0.001426797,0.0005798095,0.001196577,0.003575524],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004845319,"about_ca_system_score_gemma":0.0007237687,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005799131,"about_ca_topic_score_gemma":0.001011663,"domain_scores_codex":[0.9999157,0.00001076952,0.00001041555,0.00001785073,0.00003124414,0.00001407694],"domain_scores_gemma":[0.9998913,0.00003327103,0.00001854938,0.00000375437,0.00003354352,0.0000195509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009224816,0.00004917382,0.0001722315,0.01327837,0.00006085455,0.000207146,0.00006137433,0.0002306434,0.004059089,0.005005425,0.02682266,0.9499608],"study_design_scores_gemma":[0.000006763673,0.00005026506,0.0003782231,0.001077395,0.00003661844,0.0005495777,0.00004335462,0.00004189534,0.0005075424,0.00146545,0.9958332,0.000009748313],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001612762,0.9981232,0.0001253652,0.0002523875,0.0002408776,0.000002299532,0.00001924662,0.000008745054,0.00106654],"genre_scores_gemma":[0.0007579958,0.9977689,0.0001383034,0.0001507106,0.0001908262,0.000003515178,0.00003283909,0.000001622298,0.0009551824],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003656881,"threshold_uncertainty_score":0.01223356,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1054263159819686,"score_gpt":0.3816747237616853,"score_spread":0.2762484077797167,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}