{"id":"W2991572347","doi":"10.1111/apa.15075","title":"Encouraging prospects for paediatric drug development in Europe","year":2019,"lang":"en","type":"letter","venue":"Acta Paediatrica","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Agency (philosophy); Parliament; Off-label use; Family medicine; Legislature; Pharmaceutical industry; Food and drug administration; Pediatrics; Environmental health; Law; Pharmacology; Political science; Politics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005980831,0.0004875682,0.0008518911,0.0003939755,0.0001288545,0.00006174015,0.0003090364,0.0003930597,0.0001245402],"category_scores_gemma":[0.001216714,0.0003999097,0.0001731254,0.0009626672,0.00003285881,0.0001439654,0.0002354695,0.002250897,0.0003038823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002809999,"about_ca_system_score_gemma":0.0006281642,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001939344,"about_ca_topic_score_gemma":0.000004171049,"domain_scores_codex":[0.9969152,0.00009965855,0.0006604779,0.0007591372,0.0006271796,0.0009383001],"domain_scores_gemma":[0.99682,0.002050783,0.0003788406,0.0003776254,0.0002529775,0.0001197886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001118856,0.00009481851,0.008135458,0.001282297,0.0001278748,0.0003702904,0.0002526074,5.80692e-7,0.00001491213,0.000002471067,0.9842326,0.0053742],"study_design_scores_gemma":[0.001748966,0.0000957498,0.002121631,0.0000781672,0.000410101,0.00002128811,0.00001846858,0.00004187637,0.00005895675,0.00001496128,0.9949136,0.0004762764],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.003320376,0.009948558,0.00001874918,0.9689587,0.00163146,0.003260769,0.00004626076,0.0001388859,0.01267618],"genre_scores_gemma":[0.03017462,0.008364202,0.003805736,0.9212552,0.02073913,0.0005941231,0.0006241961,0.0002704514,0.0141723],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.04770352,"threshold_uncertainty_score":0.9998453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03606267002971195,"score_gpt":0.3084631148298121,"score_spread":0.2724004448001001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}