{"id":"W2991689750","doi":"","title":"Monte Carlo Simulation of Propagation of Axonal Loss Within the Optic Nerve In Leber Hereditary Optic Neuropathy","year":2017,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Leber's hereditary optic neuropathy; Optic nerve; Optic neuropathy; Monte Carlo method; Medicine; Physics; Neuroscience; Ophthalmology; Biology; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005828603,0.000443273,0.0006815139,0.0007733201,0.0009504796,0.0008431628,0.001032262,0.002193553,0.002227932],"category_scores_gemma":[0.002949985,0.000638543,0.0006813558,0.0007982285,0.001127821,0.0004289459,0.0005881097,0.000954448,0.0001715871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001983918,"about_ca_system_score_gemma":0.001812252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.07367892,"about_ca_topic_score_gemma":0.03787505,"domain_scores_codex":[0.999822,0.00005130098,0.000007897238,0.0000205582,0.00004246261,0.00005590847],"domain_scores_gemma":[0.9969804,0.002211965,0.0002135431,0.00006849812,0.0002882795,0.0002372173],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.00005761618,0.00003295402,0.001380223,0.0000117064,0.00001411393,0.00007050684,0.00002658099,0.9965064,0.0001899184,0.00115821,0.0001126892,0.0004390107],"study_design_scores_gemma":[0.00001437669,0.00001034725,0.000385716,0.000004053083,0.000004377064,0.000008903522,0.00001628477,0.9990849,0.00009683304,0.0003194861,0.00004973341,0.000005045432],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9668987,0.000492999,0.02024197,0.0006891997,0.00008245749,0.00005247159,0.000394908,0.0002439989,0.0109033],"genre_scores_gemma":[0.9933301,0.0001012639,0.004614565,0.00009582661,0.000009663572,0.00003747624,0.0001660983,0.0000329015,0.001612059],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07367892,"threshold_uncertainty_score":0.1465001,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02730096813005012,"score_gpt":0.3156980738368291,"score_spread":0.288397105706779,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}