{"id":"W2991697598","doi":"","title":"Opposing effects of HDAC inhibitors in hP23H and hT17M animal models of retinitis pigmentosa","year":2015,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Vancouver General Hospital","funders":"","keywords":"Retinitis pigmentosa; Medicine; Biology; Ophthalmology; Retinal","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000420371,0.0005859528,0.0008117968,0.0009994684,0.0003989593,0.00058388,0.0004989228,0.0007436667,0.002605045],"category_scores_gemma":[0.0002176423,0.0003369599,0.0007934103,0.000381203,0.0008952962,0.0004806219,0.0002412146,0.002453424,0.000487836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006802233,"about_ca_system_score_gemma":0.0005668203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002516368,"about_ca_topic_score_gemma":0.00643763,"domain_scores_codex":[0.9994387,0.00007580939,0.00004951866,0.0001027353,0.0001587186,0.0001744379],"domain_scores_gemma":[0.9995678,0.00005975736,0.0001008539,0.00006034131,0.00003075541,0.000180542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006310052,0.0007187932,0.0004492117,0.0001326413,0.00006737151,0.0002782725,0.00005502174,0.000256936,0.9843924,0.0003730562,0.0004052994,0.006560969],"study_design_scores_gemma":[0.0005503101,0.005641299,0.005587716,0.00002277876,0.0001701073,0.0004008278,0.0001982643,0.000683476,0.9829055,0.000185229,0.003629612,0.00002481491],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920743,0.003080439,0.0007702418,0.000415785,0.0002213229,0.00005346099,0.0008627353,0.0001536532,0.002368164],"genre_scores_gemma":[0.9891964,0.002347686,0.001536468,0.0001405409,0.00006674464,0.0001190475,0.0005649859,0.00005652192,0.005971576],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002605045,"threshold_uncertainty_score":0.008714736,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03153836213133799,"score_gpt":0.3089175184431159,"score_spread":0.2773791563117779,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}