{"id":"W2991697598","doi":"","title":"Opposing effects of HDAC inhibitors in hP23H and hT17M animal models of retinitis pigmentosa","year":2015,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Vancouver General Hospital","funders":"","keywords":"Retinitis pigmentosa; Medicine; Biology; Ophthalmology; Retinal","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0005533163,0.0001367771,0.0002081949,0.0001345316,0.00004635127,0.00001019136,0.0001932981,0.0001021334,0.000001763799],"category_scores_gemma":[0.0006086572,0.0001299146,0.00002541678,0.000394096,0.002725291,0.00002826553,0.0002495082,0.00007435194,6.259738e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001930153,"about_ca_system_score_gemma":0.0003585285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009453658,"about_ca_topic_score_gemma":0.000003090877,"domain_scores_codex":[0.9987363,0.000118559,0.0002739501,0.0003785181,0.000232905,0.0002597694],"domain_scores_gemma":[0.99937,0.00004012059,0.000156687,0.0001091242,0.000155898,0.0001681922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006818284,0.00005322834,0.08557426,0.00003197928,0.000006154888,0.00001692268,0.0006998692,0.00002704835,0.9132087,0.0001237367,0.00001936393,0.0001705311],"study_design_scores_gemma":[0.000507185,0.001337528,0.05986797,0.0000831275,0.000005326201,0.00003751576,0.0003617667,0.0002161703,0.9345319,0.002907661,0.000006376012,0.0001375329],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971284,0.0004634626,0.000009562196,0.00006387106,0.00008118332,0.000187817,0.000001979075,0.00000292882,0.002060854],"genre_scores_gemma":[0.9986284,0.00002110262,0.001253941,0.00003807192,0.00001474006,0.00001107307,0.000004974432,0.000007135811,0.00002058328],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02570629,"threshold_uncertainty_score":0.9999887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03153836213133799,"score_gpt":0.3089175184431159,"score_spread":0.2773791563117779,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}