{"id":"W2991701263","doi":"10.1126/science.aax1323","title":"Embryonal precursors of Wilms tumor","year":2019,"lang":"en","type":"article","venue":"Science","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":159,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Oncode Institute; Little Princess Trust; Cambridge University Hospitals; Royal College of Surgeons of England; National Institute for Health and Care Research; St. Baldrick's Foundation; University of Cambridge; Cancer Research UK; Hospital for Sick Children; Wellcome Trust; Wellcome","keywords":"Wilms' tumor; Somatic cell; Biology; Mutant; Cancer; Pathology; Kidney; Cancer research; Mutation; Genetics; Medicine; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001475433,0.0002044751,0.0001654474,0.000413921,0.0003101935,0.0005094976,0.0002426788,0.0004466893,0.002264574],"category_scores_gemma":[0.0005838055,0.0002096643,0.0001136737,0.0001299644,0.000204623,0.0002886119,0.0003343777,0.0008121259,0.001275713],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004303398,"about_ca_system_score_gemma":0.0003861142,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001070108,"about_ca_topic_score_gemma":0.00169039,"domain_scores_codex":[0.9999171,0.00001044752,0.000006190625,0.0000135601,0.00003564579,0.00001703305],"domain_scores_gemma":[0.9996407,0.00006790224,0.00004771727,0.00004962777,0.00009236571,0.0001016825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007172399,0.0001001296,0.03856413,0.0005171893,0.00006429435,0.03018291,0.00118168,0.001214401,0.7242224,0.08750031,0.02209197,0.09364342],"study_design_scores_gemma":[0.00007343536,0.0003247445,0.1224109,0.000172422,0.00005181745,0.04051735,0.000368081,0.001715292,0.3075843,0.01239621,0.5143373,0.00004819606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.80446,0.04828076,0.0281373,0.002598457,0.001271589,0.0002647856,0.0049062,0.000915485,0.1091654],"genre_scores_gemma":[0.9582385,0.01204108,0.006248347,0.0004348585,0.0002398603,0.00005605171,0.001924752,0.00006673454,0.02074968],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002264574,"threshold_uncertainty_score":0.00757581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002079929562024485,"score_gpt":0.2142976675304326,"score_spread":0.2122177379684081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}