{"id":"W2991701263","doi":"10.1126/science.aax1323","title":"Embryonal precursors of Wilms tumor","year":2019,"lang":"en","type":"article","venue":"Science","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":159,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Oncode Institute; Little Princess Trust; Cambridge University Hospitals; Royal College of Surgeons of England; National Institute for Health and Care Research; St. Baldrick's Foundation; University of Cambridge; Cancer Research UK; Hospital for Sick Children; Wellcome Trust; Wellcome","keywords":"Wilms' tumor; Somatic cell; Biology; Mutant; Cancer; Pathology; Kidney; Cancer research; Mutation; Genetics; Medicine; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001149157,0.00003715405,0.0000429776,0.00002151167,0.00002374827,0.000005158166,0.00019933,0.00002177351,0.00002896705],"category_scores_gemma":[0.0000169486,0.0000274817,0.00002669463,0.0001434107,0.0002475537,0.000002818473,0.00004944557,0.00003006003,0.00002646083],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005040104,"about_ca_system_score_gemma":0.0001507178,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004649573,"about_ca_topic_score_gemma":7.427227e-7,"domain_scores_codex":[0.9995208,0.000004806956,0.00006061177,0.0001624214,0.0001352196,0.0001161346],"domain_scores_gemma":[0.9997467,0.000001624004,0.00003404896,0.0001375963,0.00004262948,0.00003740727],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001192638,0.000006578273,0.003029407,0.000005704452,0.000002885393,2.494174e-7,0.00001511796,0.0001684925,0.9959604,0.00009872576,0.0001345582,0.0005659618],"study_design_scores_gemma":[0.0001336654,0.0001614698,0.007009815,0.00001438768,0.000001956561,0.00000789301,0.00003544009,0.00008807723,0.9844244,0.00006702897,0.00799348,0.0000623533],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988737,0.0002821524,0.0000180101,0.00002947256,0.0002351428,0.00004778811,0.000002012897,0.000002247348,0.0106462],"genre_scores_gemma":[0.9977791,0.00002693712,0.000127503,0.00007902181,0.000023579,0.000001169275,0.000001397976,0.000002253607,0.00195905],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01153596,"threshold_uncertainty_score":0.1120671,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002079929562024485,"score_gpt":0.2142976675304326,"score_spread":0.2122177379684081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}