{"id":"W2991728991","doi":"10.1172/jci.insight.132377","title":"MEK1 regulates pulmonary macrophage inflammatory responses and resolution of acute lung injury","year":2019,"lang":"en","type":"article","venue":"JCI Insight","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; University of Washington; National Institutes of Health; Cystic Fibrosis Foundation","keywords":"ARDS; Alveolar macrophage; Inflammation; Proinflammatory cytokine; Macrophage; Medicine; Lung; Immunology; Myeloid; Myeloid cells; Internal medicine; Biology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009975085,0.0002339448,0.0001535852,0.0002150201,0.0001541065,0.0002780175,0.0001251643,0.0001528032,0.0007754815],"category_scores_gemma":[0.0001129888,0.00009875358,0.0001448269,0.00005749408,0.0001410121,0.00012748,0.0001947777,0.0004879692,0.000283921],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003016278,"about_ca_system_score_gemma":0.0002417589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004883056,"about_ca_topic_score_gemma":0.0009899499,"domain_scores_codex":[0.9998959,0.00001840045,0.000006911133,0.00001593993,0.00001979119,0.00004306958],"domain_scores_gemma":[0.9999352,0.000004625349,0.0000189,0.000003603621,0.00001071389,0.00002698763],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008855503,0.00009232385,0.003188733,0.00007964698,0.00001021264,0.0001588056,0.00004485264,0.0001407767,0.9880216,0.0002398291,0.0001971177,0.006940437],"study_design_scores_gemma":[0.000140009,0.0009874551,0.1542588,0.00003692073,0.00005122769,0.001353459,0.0002315921,0.002392734,0.8331127,0.0003794217,0.007039648,0.00001609861],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938623,0.003400921,0.000981463,0.0001726804,0.00001759757,0.00001969902,0.000173912,0.00005435599,0.001316985],"genre_scores_gemma":[0.9977096,0.0008430253,0.0004792962,0.00002728819,0.00000866998,0.00001159207,0.00009091789,0.000004480494,0.0008250287],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007754815,"threshold_uncertainty_score":0.002594233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005008221971954383,"score_gpt":0.2274790433641361,"score_spread":0.2224708213921817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}