{"id":"W2991887382","doi":"10.1080/13813455.2019.1694039","title":"PNPLA3 and IL 28B signature for predicting susceptibility to chronic hepatitis C infection and fibrosis progression","year":2019,"lang":"en","type":"article","venue":"Archives of Physiology and Biochemistry","topic":"Hepatitis C virus research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Science and Technology Development Fund","keywords":"Fibrosis; Genotype; Haplotype; Hepatitis C virus; Genetic predisposition; Immunology; Interleukin 28B; Single-nucleotide polymorphism; Internal medicine; Biology; Medicine; Genetics; Gene; Virus; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008495291,0.00009803437,0.0002098562,0.00003658808,0.00006125966,0.000005432468,0.00003055259,0.0001175624,0.0000271953],"category_scores_gemma":[0.0001673684,0.00008075104,0.00003219372,0.00004439436,0.000250074,0.00003058381,0.0001245477,0.0001583,7.640213e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001139149,"about_ca_system_score_gemma":0.00005470128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006303161,"about_ca_topic_score_gemma":0.000026972,"domain_scores_codex":[0.9992738,0.00002767568,0.0001272574,0.0003302075,0.00006926205,0.0001717838],"domain_scores_gemma":[0.9994391,0.0002328249,0.00004510732,0.0001475394,0.00003161104,0.0001038247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000254386,0.0000271943,0.3078512,0.001415017,0.00002139197,2.65789e-7,0.00008695128,5.95095e-7,0.666117,0.000002635259,0.00003656163,0.02418688],"study_design_scores_gemma":[0.0006131506,0.001021614,0.4358628,0.0002802581,0.00001555352,0.00000493125,0.00001274969,0.0005083157,0.5612475,0.0001634846,0.0002039452,0.00006566788],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985096,0.0005223434,0.00002218688,0.0001708418,0.00002087633,0.0004716421,0.00007672247,0.00001495556,0.0001908428],"genre_scores_gemma":[0.998359,0.0005792793,0.0006844371,0.00003327078,0.0000862001,0.00003134965,0.00008042834,0.000007895088,0.000138122],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1280116,"threshold_uncertainty_score":0.3292932,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0074156084788478,"score_gpt":0.2916263065058615,"score_spread":0.2842106980270137,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}