{"id":"W2991923932","doi":"10.1098/rsob.190198","title":"Efficiency of RNA interference is improved by knockdown of dsRNA nucleases in tephritid fruit flies","year":2019,"lang":"en","type":"article","venue":"Open Biology","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Hort Innovation; Commonwealth Scientific and Industrial Research Organisation","keywords":"Biology; RNA interference; RNA silencing; Gene knockdown; RNA; Interference (communication); Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001176708,0.0001201877,0.0002669927,0.00003943862,0.00001558596,0.000008277878,0.0005533561,0.0001736346,0.0002334447],"category_scores_gemma":[0.00003897194,0.0001059771,0.0000539249,0.00008579111,0.0001465067,0.000003645666,0.0003168764,0.00006572503,0.0000114587],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006511457,"about_ca_system_score_gemma":0.00007350445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002883026,"about_ca_topic_score_gemma":0.0001444334,"domain_scores_codex":[0.9991137,0.00005193072,0.0002957493,0.0002947486,0.00003651578,0.0002073409],"domain_scores_gemma":[0.9993894,0.00001682343,0.0001415949,0.0003497036,0.00007574433,0.00002677549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000179981,0.00009142757,0.01066803,0.00002854626,0.00001955562,2.145213e-7,0.00007306556,0.000001223966,0.9840895,0.00008385192,0.0008246417,0.003939989],"study_design_scores_gemma":[0.0006718806,0.0009573136,0.002524146,0.00003268304,0.000005287361,0.000001571632,0.0001401945,0.00001747333,0.9858387,0.0001234699,0.009548727,0.0001385863],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909799,0.001357067,0.00005158542,0.00005838819,0.00008724278,0.0002667004,0.0001238983,0.000001722514,0.007073475],"genre_scores_gemma":[0.9979463,0.0005149339,0.000323445,0.000205278,0.00001694024,0.000009937557,0.00006814723,0.000009686267,0.0009052884],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008724086,"threshold_uncertainty_score":0.4321619,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006937156198836445,"score_gpt":0.2635251314335306,"score_spread":0.2565879752346942,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}