{"id":"W2991923932","doi":"10.1098/rsob.190198","title":"Efficiency of RNA interference is improved by knockdown of dsRNA nucleases in tephritid fruit flies","year":2019,"lang":"en","type":"article","venue":"Open Biology","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Hort Innovation; Commonwealth Scientific and Industrial Research Organisation","keywords":"Biology; RNA interference; RNA silencing; Gene knockdown; RNA; Interference (communication); Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001804623,0.0004758768,0.00029932,0.0002680135,0.0001304373,0.0003799093,0.0002450929,0.0003249011,0.0007259519],"category_scores_gemma":[0.0001504209,0.0001796626,0.0002676234,0.0001110668,0.0001946971,0.0002406768,0.0002623228,0.0005055209,0.0002355534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002824379,"about_ca_system_score_gemma":0.0001266289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009643243,"about_ca_topic_score_gemma":0.001266341,"domain_scores_codex":[0.9998462,0.00002372142,0.00002530913,0.00004362467,0.00004136833,0.00001975924],"domain_scores_gemma":[0.9998531,0.00002986403,0.00005778907,0.00001436926,0.0000145619,0.00003032003],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001053236,0.000004329647,0.0000574126,0.00001091045,0.000001799834,0.000009791266,0.000005586556,0.0000199265,0.9996069,0.00002116112,0.000004391191,0.0002472826],"study_design_scores_gemma":[0.000009444199,0.0001161873,0.003487879,0.000005075056,0.00001128296,0.00007099684,0.00001507411,0.001081221,0.9943897,0.00001293557,0.0007955928,0.000004618169],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934999,0.0006178439,0.00413658,0.0000531487,0.00001697391,0.00004148196,0.000215612,0.0000992458,0.001319073],"genre_scores_gemma":[0.9924842,0.0005881425,0.003798433,0.00003261934,0.000005379386,0.00005698682,0.0003444794,0.00004812947,0.002641796],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009643243,"threshold_uncertainty_score":0.002428532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006937156198836445,"score_gpt":0.2635251314335306,"score_spread":0.2565879752346942,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}