{"id":"W2992243625","doi":"10.3390/pharmaceutics11120664","title":"Monitoring the Clinical Response to an Innovative Transdermal Delivery System for Ibuprofen","year":2019,"lang":"en","type":"article","venue":"Pharmaceutics","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Department of Industry and Science, Australian Government","keywords":"Transdermal; Ibuprofen; Medicine; Delivery system; Pharmacology; Intensive care medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002642164,0.0001590192,0.0003060223,0.00007664281,0.0001105373,0.00001917696,0.0001622309,0.000106281,0.00001261402],"category_scores_gemma":[0.0001729052,0.0001107458,0.00009709998,0.0002584692,0.00004091946,0.00008912054,0.00003373584,0.0003604154,0.0001287705],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009931467,"about_ca_system_score_gemma":0.0002040325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002577792,"about_ca_topic_score_gemma":3.957583e-7,"domain_scores_codex":[0.9984254,0.0003273225,0.0003997666,0.0002534693,0.0002544808,0.0003395251],"domain_scores_gemma":[0.9981949,0.00082442,0.00007715067,0.0003433828,0.0003136735,0.0002464725],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.05303217,0.0004466845,0.4233075,0.001901666,0.0005820903,0.0001718461,0.01054321,0.0001447819,0.4271649,0.0002455232,0.001211506,0.08124815],"study_design_scores_gemma":[0.01408154,0.003254839,0.1974688,0.0008023063,0.0005645785,0.00009809722,0.003968646,0.01089257,0.6082429,0.000005635227,0.159972,0.0006480932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937813,0.0001188303,0.000249824,0.0008662138,0.002637675,0.002098979,0.00001979563,0.00009809529,0.0001293082],"genre_scores_gemma":[0.9968091,0.00001573504,0.0005725904,0.0009464553,0.001311926,0.0001100203,0.00000595466,0.0000390895,0.0001891831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2258388,"threshold_uncertainty_score":0.4516081,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1058814744590354,"score_gpt":0.4438034181235317,"score_spread":0.3379219436644962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}