{"id":"W2992279139","doi":"10.1182/blood.v112.11.1374.1374","title":"The Cbl E3 Ubiquitin Ligase Negatively Regulates Erythropoiesis through Expression of the Foxo3a Transcription Factor.","year":2008,"lang":"en","type":"article","venue":"Blood","topic":"Kruppel-like factors research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Erythropoiesis; Erythropoietin; Biology; Signal transduction; Erythropoietin receptor; Cell biology; Stem cell factor; Ubiquitin ligase; Thrombopoiesis; Progenitor cell; Transferrin receptor; Megakaryocyte; Molecular biology; Endocrinology; Internal medicine; Stem cell; Ubiquitin; Transferrin; Anemia; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001009751,0.0002489162,0.0001365877,0.0002337689,0.0002935592,0.0002557749,0.0002542446,0.0002424544,0.004737046],"category_scores_gemma":[0.00007557051,0.0001237393,0.0002940289,0.000156411,0.0004009983,0.000149846,0.0002640658,0.0005141934,0.0008039584],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000706025,"about_ca_system_score_gemma":0.000337448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002517206,"about_ca_topic_score_gemma":0.003971779,"domain_scores_codex":[0.9998819,0.000007720192,0.000005383783,0.00003831167,0.00002910943,0.00003765143],"domain_scores_gemma":[0.9999204,0.00000529862,0.00002582608,0.000007982339,0.000008561628,0.00003190297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001185705,0.00001836094,0.0003932562,0.00003988577,0.000003668184,0.00003790767,0.00000816111,0.00003449782,0.9974123,0.0002345407,0.0002768782,0.001421966],"study_design_scores_gemma":[0.00008573601,0.0001327802,0.01676011,0.00002738965,0.00002565187,0.0003326652,0.00005294363,0.001930809,0.9671385,0.0002274031,0.0132746,0.00001151938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9785865,0.004638487,0.005581425,0.0006371874,0.000240968,0.00004775447,0.00242624,0.0005005225,0.00734085],"genre_scores_gemma":[0.9858972,0.0006897617,0.001713082,0.0001709202,0.00001417467,0.00003307662,0.0009644071,0.00004794831,0.01046926],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004737046,"threshold_uncertainty_score":0.01584703,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02283071541915626,"score_gpt":0.2608186575831832,"score_spread":0.237987942164027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}