{"id":"W2992401849","doi":"10.1002/jlb.4ma1019-152r","title":"IFNγ receptor down-regulation facilitates <i>Legionella</i> survival in alveolar macrophages","year":2019,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Infection and Immunity; National Institute of Allergy and Infectious Diseases; National Health and Medical Research Council; National Institutes of Health; University of Melbourne; Medical Research Council; Australian Government","keywords":"Legionella pneumophila; Biology; Microbiology; Secretion; Intracellular; Phagosome; Legionella; Effector; Phagocytosis; Intracellular parasite; Cell biology; Receptor; Vacuole; Type three secretion system; Bacteria; Virulence; Gene; Cytoplasm","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000230948,0.0003408816,0.0004443086,0.000153214,0.0001555361,0.000417636,0.000202298,0.0003830991,0.001043887],"category_scores_gemma":[0.0001272568,0.0001398658,0.0003903891,0.00009918488,0.0002367208,0.0001897165,0.0002031174,0.0008512889,0.0005940243],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002760247,"about_ca_system_score_gemma":0.0002110164,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004766122,"about_ca_topic_score_gemma":0.0005306739,"domain_scores_codex":[0.9996593,0.00005410456,0.00004453662,0.0000629595,0.00005310876,0.0001258991],"domain_scores_gemma":[0.9998431,0.00002465783,0.00004836972,0.00002443034,0.00002392051,0.00003539166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001687063,0.00002504462,0.0001759725,0.00003672648,0.000003043778,0.0000493961,0.0000215088,0.00002457202,0.9988781,0.00003016745,0.00004146783,0.0005452133],"study_design_scores_gemma":[0.00003672478,0.0004465612,0.007073213,0.00001659699,0.00002469968,0.0002615593,0.00008402765,0.0005168695,0.9888102,0.00004573199,0.002677715,0.000006042339],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943356,0.00191154,0.001312668,0.0002409448,0.00006845467,0.00002921159,0.0003759915,0.0001225079,0.00160301],"genre_scores_gemma":[0.9956139,0.0007855673,0.00097851,0.0001932337,0.00002287275,0.00003730797,0.0004033851,0.00002549871,0.001939678],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001043887,"threshold_uncertainty_score":0.003492117,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01233458697808114,"score_gpt":0.2730440638029001,"score_spread":0.260709476824819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}