{"id":"W2992401849","doi":"10.1002/jlb.4ma1019-152r","title":"IFNγ receptor down-regulation facilitates <i>Legionella</i> survival in alveolar macrophages","year":2019,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Infection and Immunity; National Institute of Allergy and Infectious Diseases; National Health and Medical Research Council; National Institutes of Health; University of Melbourne; Medical Research Council; Australian Government","keywords":"Legionella pneumophila; Biology; Microbiology; Secretion; Intracellular; Phagosome; Legionella; Effector; Phagocytosis; Intracellular parasite; Cell biology; Receptor; Vacuole; Type three secretion system; Bacteria; Virulence; Gene; Cytoplasm","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007106686,0.0001647513,0.0003276063,0.0001669368,0.00003721175,0.00001929612,0.0003119481,0.0002647359,0.0001249126],"category_scores_gemma":[0.0001095295,0.0001306833,0.0001692274,0.0001460029,0.0001187411,0.00001379264,0.0001018039,0.0002662321,0.00009702595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005342562,"about_ca_system_score_gemma":0.0001761162,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004189264,"about_ca_topic_score_gemma":0.00001948454,"domain_scores_codex":[0.9984966,0.0002449736,0.0004885346,0.0002604643,0.0001676871,0.0003417553],"domain_scores_gemma":[0.999158,0.00006108024,0.0002406271,0.0002309639,0.0002082463,0.0001010314],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004995324,0.00006267202,0.0763068,0.00001869886,0.00005575053,0.00000836489,0.00005561644,0.0001247116,0.9195992,0.00009966614,0.001806979,0.001362029],"study_design_scores_gemma":[0.004799586,0.002346487,0.04794029,0.00006065875,0.00001835854,0.0001516922,0.0003976781,0.00008335998,0.6442524,0.0005496623,0.2989441,0.0004557746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954706,0.002208926,0.0001670675,0.0005722126,0.000710479,0.00014035,0.00001088169,0.000003986316,0.0007154817],"genre_scores_gemma":[0.9966385,0.001203718,0.0002938108,0.0001381097,0.0004596258,0.000002381075,0.00005154254,0.00001605895,0.001196191],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2971371,"threshold_uncertainty_score":0.5329111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01233458697808114,"score_gpt":0.2730440638029001,"score_spread":0.260709476824819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}