{"id":"W2992543001","doi":"10.1080/10937404.2019.1642586","title":"Concordance between sites of tumor development in humans and in experimental animals for 111 agents that are carcinogenic to humans","year":2019,"lang":"en","type":"review","venue":"Journal of Toxicology and Environmental Health Part B","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; University of Ottawa","funders":"National Institute of Environmental Health Sciences; World Health Organization","keywords":"Carcinogen; Concordance; Physiology; Cancer; Medicine; Larynx; Pathology; Toxicology; Internal medicine; Oncology; Biology; Surgery; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005781061,0.0002740187,0.001324957,0.0001637094,0.0000659581,0.000006779572,0.0001485735,0.0002201266,0.00001485223],"category_scores_gemma":[0.000008648813,0.0002532278,0.0001504691,0.00003917978,0.00008829377,0.000006055523,0.0001489156,0.000214051,9.674917e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002758779,"about_ca_system_score_gemma":0.0001997666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001002091,"about_ca_topic_score_gemma":0.000240777,"domain_scores_codex":[0.9980511,0.0001632229,0.0009612537,0.000353858,0.0001386509,0.0003319293],"domain_scores_gemma":[0.9988471,0.00004852696,0.0007920756,0.0001425833,0.000007251673,0.0001625123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001246441,0.001983749,0.8566778,0.02227348,0.0008955984,0.0001136577,0.002739591,0.00006046955,0.03694212,0.00001569507,0.002523258,0.07452817],"study_design_scores_gemma":[0.002813555,0.005810034,0.2097144,0.00330465,0.0001620059,0.0001199874,0.001192503,0.000001319735,0.01277841,0.00000606123,0.7634469,0.0006502384],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.547598,0.451607,0.000004697712,0.00002599962,0.00005537843,0.0006028454,0.0001030616,3.557674e-7,0.000002639278],"genre_scores_gemma":[0.5478967,0.4514401,0.0002190821,0.000200666,0.00007067895,0.00004171462,0.00006883728,0.0000188848,0.00004333808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7609236,"threshold_uncertainty_score":0.999992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09869786111681647,"score_gpt":0.3801779656572156,"score_spread":0.2814801045403991,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}