{"id":"W2992834502","doi":"10.3390/plants8120567","title":"Optimize, Modulate, and Scale-up Resveratrol and Resveratrol Dimers Bioproduction in Vitis labrusca L. Cell Suspension from Flasks to 20 L Bioreactor","year":2019,"lang":"en","type":"article","venue":"Plants","topic":"Sirtuins and Resveratrol in Medicine","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Brock University; Conseil Régional Champagne Ardenne","keywords":"Resveratrol; Bioproduction; Chemistry; Bioreactor; Suspension culture; Methyl jasmonate; Suspension (topology); Cell culture; Chromatography; Biochemistry; Organic chemistry; Biology; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002713007,0.0002970234,0.0006029725,0.00034129,0.00007300769,0.00004390568,0.00007698203,0.0002362374,0.0002054907],"category_scores_gemma":[0.00005521971,0.0002351526,0.00004501029,0.0002201773,0.00007529779,0.000150106,0.00008484688,0.000385988,0.00009877917],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006566928,"about_ca_system_score_gemma":0.00004592659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001097378,"about_ca_topic_score_gemma":0.0001842133,"domain_scores_codex":[0.9980127,0.00006779444,0.0003485002,0.0007679043,0.0003864724,0.0004166269],"domain_scores_gemma":[0.9989484,0.0001052873,0.0000848725,0.000432206,0.00006381743,0.0003654394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.003008864,0.0001314706,0.117544,0.00009189278,0.00006564783,0.0001691925,0.0008503479,0.0001083408,0.8627505,0.000002302186,0.01089318,0.00438426],"study_design_scores_gemma":[0.03043989,0.00278368,0.753344,0.001707399,0.0003782369,0.0004650978,0.001873355,0.01147982,0.1774598,0.00006368969,0.01873886,0.001266121],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940745,0.00152642,0.00001186364,0.001710698,0.0009347174,0.000931483,0.0001085446,0.00005360154,0.0006481434],"genre_scores_gemma":[0.9937713,0.001149267,0.001037885,0.0006553664,0.0004557401,0.00001438944,0.0001911967,0.00004219973,0.002682654],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6852906,"threshold_uncertainty_score":0.9589245,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006872896634494089,"score_gpt":0.2242598007167321,"score_spread":0.217386904082238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}