{"id":"W2992856652","doi":"10.1038/s41419-019-2134-8","title":"Intramitochondrial Src kinase links mitochondrial dysfunctions and aggressiveness of breast cancer cells","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Moncton","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Tel Aviv University; New Brunswick Innovation Foundation; Fondation de la recherche en santé du Nouveau-Brunswick; Université de Moncton; Cancer Research Institute","keywords":"Mitochondrion; Biology; Proto-oncogene tyrosine-protein kinase Src; Cell biology; Kinase; Subcellular localization; Cancer research; Cancer cell; Mitochondrial DNA; Cancer; Biochemistry; Cytoplasm; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001037914,0.0001938295,0.0002000886,0.0002421156,0.0001436788,0.0002594233,0.0001010934,0.0001942906,0.001176034],"category_scores_gemma":[0.0001276099,0.00008590206,0.0001133907,0.0001732505,0.0001322885,0.0001346219,0.000195083,0.0004225252,0.0002097043],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000172205,"about_ca_system_score_gemma":0.000146431,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003942513,"about_ca_topic_score_gemma":0.0005278408,"domain_scores_codex":[0.9999131,0.0000136262,0.000006891461,0.0000126671,0.00002948043,0.00002424624],"domain_scores_gemma":[0.9998962,0.00001087529,0.00004048484,0.000008364707,0.00001877871,0.00002527419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004890612,0.00009265178,0.005070985,0.00008791842,0.00001994337,0.0003463949,0.00005860272,0.00008846224,0.987267,0.0001638708,0.0001642019,0.006151035],"study_design_scores_gemma":[0.00005363876,0.001192668,0.2121531,0.0000222753,0.00008724825,0.003447193,0.0003453627,0.002003127,0.7738878,0.0004403081,0.006352987,0.00001436403],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939438,0.003723342,0.0008140389,0.0001529312,0.00001966703,0.00001134164,0.0001217584,0.00003324389,0.001179917],"genre_scores_gemma":[0.9977743,0.001166898,0.0001465264,0.00002111799,0.000006235457,0.000006622764,0.0001366556,0.000002262999,0.0007393947],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001176034,"threshold_uncertainty_score":0.003934205,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005671351089258721,"score_gpt":0.221343824396793,"score_spread":0.2156724733075343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}