{"id":"W2992878015","doi":"10.1016/j.phymed.2019.152846","title":"Supercritical CO2 fluid extraction of croton crassifolius Geisel root: Chemical composition and anti-proliferative, autophagic, apoptosis-inducing, and related molecular effects on A549 tumour cells","year":2019,"lang":"en","type":"article","venue":"Phytomedicine","topic":"Bioactive Natural Diterpenoids Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ministry of Agriculture","funders":"","keywords":"Apoptosis; Cell cycle; Essential oil; Cell growth; A549 cell; Chemistry; Flow cytometry; Western blot; Nutraceutical; Cell cycle checkpoint; Thymoquinone; Biology; Traditional medicine; Biochemistry; Molecular biology; Food science; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001893009,0.00021441,0.0003229002,0.0001061488,0.00004640524,0.00001878027,0.00009071716,0.0002791281,0.0000401484],"category_scores_gemma":[0.00008615542,0.0001865088,0.00005417538,0.0001245967,0.000221344,0.00001490237,0.00008612742,0.0003607635,0.00001044628],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000292724,"about_ca_system_score_gemma":0.00003019381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000132282,"about_ca_topic_score_gemma":2.945274e-7,"domain_scores_codex":[0.9985418,0.0001309854,0.0002421666,0.0004965871,0.0003099844,0.0002785217],"domain_scores_gemma":[0.9993577,0.0000818281,0.00003937916,0.0002180296,0.0001404557,0.0001625969],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002997484,0.0001317354,0.001069916,0.0002419141,0.0000652029,0.00001420515,0.00003453797,0.000002322383,0.9972886,0.00003575277,0.0002004305,0.0006156121],"study_design_scores_gemma":[0.001678539,0.0009094694,0.02092355,0.0001692472,0.00004067754,0.00005318222,0.0000165467,0.0003102079,0.9756153,0.00002793397,0.00007869738,0.0001766925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971977,0.0008758222,0.00007990485,0.0003930176,0.0001634825,0.0005961311,0.00001650877,0.00001442773,0.0006629614],"genre_scores_gemma":[0.999283,0.0001240245,0.0001073458,0.0001546019,0.0001235516,0.00002221521,0.0001133648,0.00002666703,0.00004522217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02167336,"threshold_uncertainty_score":0.7605606,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00493036318937674,"score_gpt":0.2732714090830644,"score_spread":0.2683410458936877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}