{"id":"W2992975791","doi":"10.1182/blood.v112.11.3099.3099","title":"BMI1 Interacts with FANCD2 at DNA Lesions and Prevents Chromosome Breaks","year":2008,"lang":"en","type":"article","venue":"Blood","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont; Institute for Research in Immunology and Cancer","funders":"","keywords":"BMI1; Biology; FANCD2; DNA damage; DNA repair; Stem cell; Chromatin; Fanconi anemia; Cell biology; Cell cycle; Cancer research; Genetics; Cell; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001224452,0.0002532867,0.0002018996,0.0003444064,0.0001790474,0.0002168339,0.0002227194,0.0002479108,0.002193496],"category_scores_gemma":[0.0001660029,0.0001620042,0.0002301918,0.0001441474,0.0001535513,0.0001274321,0.0003093716,0.0003781376,0.0008019002],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003813879,"about_ca_system_score_gemma":0.0001220671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006438114,"about_ca_topic_score_gemma":0.0007786371,"domain_scores_codex":[0.9998733,0.00001403561,0.000007463076,0.0000341441,0.00004160411,0.00002937867],"domain_scores_gemma":[0.9998914,0.00001230729,0.00002355865,0.000008197452,0.00001090615,0.00005368518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008604738,0.000007787969,0.0002287426,0.00003019611,0.000004195396,0.00001909659,0.000004191149,0.00002176679,0.9990397,0.0000295462,0.00004910609,0.0004796126],"study_design_scores_gemma":[0.00002499415,0.0001443669,0.0199088,0.00001293874,0.00001286837,0.000441013,0.00001920955,0.001209277,0.9734914,0.00003685682,0.004691749,0.000006592259],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916727,0.002748331,0.002619391,0.0000894875,0.00003697384,0.00003671366,0.0006265262,0.0001448442,0.002025101],"genre_scores_gemma":[0.9922761,0.0006927375,0.001842171,0.00007808751,0.00001300724,0.00004861102,0.00145451,0.00003302246,0.003561706],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002193496,"threshold_uncertainty_score":0.007338047,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00822683061087612,"score_gpt":0.2142421978269938,"score_spread":0.2060153672161177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}