{"id":"W2993113471","doi":"10.1182/blood.v110.11.1950.1950","title":"No Significance of Derivative Chromosome 9 Deletion on the Clearance Kinetics of BCR/ABL Fusion Transcripts, Cytogenetic or Molecular Response, Loss of Response or Treatment Failure to Imatinib Mesylate Therapy for Chronic Myeloid Leukemia.","year":2007,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network; Princess Margaret Cancer Centre","funders":"","keywords":"Imatinib mesylate; Internal medicine; Medicine; Imatinib; Myeloid leukemia; breakpoint cluster region; Oncology; Philadelphia chromosome; Gastroenterology; Immunology; Chromosomal translocation; Biology; Genetics; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000616208,0.000103231,0.0002226926,0.0001502794,0.00007885871,0.0001598025,0.00010808,0.0002033676,0.001761613],"category_scores_gemma":[0.0009070297,0.00005105895,0.000165124,0.00008637831,0.0001838247,0.0001384524,0.0001175006,0.0002354248,0.0002272699],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002034524,"about_ca_system_score_gemma":0.0001159308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002124299,"about_ca_topic_score_gemma":0.0002229164,"domain_scores_codex":[0.9997275,0.00009155284,0.00002465496,0.00006259905,0.00005169717,0.00004192682],"domain_scores_gemma":[0.9988945,0.0005336918,0.0002595832,0.0000765016,0.00007498752,0.0001607362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01971793,0.0004645212,0.7774383,0.0001681547,0.0001882261,0.001457825,0.0002748318,0.0007857694,0.1636492,0.0001251041,0.0002902564,0.03543986],"study_design_scores_gemma":[0.0001221612,0.007234082,0.9732616,0.00000483127,0.00008226105,0.002087357,0.00006933082,0.000767334,0.01521282,0.00003383099,0.001118223,0.000006141793],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989454,0.0003315637,0.00009690746,0.00001265145,0.000002462943,0.000009854601,0.00009532092,0.000004118353,0.0005016654],"genre_scores_gemma":[0.9996973,0.00001853097,0.000029649,0.00000762423,0.000002085096,0.000005361125,0.0001027677,9.787907e-7,0.0001357159],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001761613,"threshold_uncertainty_score":0.005893171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02582337342119892,"score_gpt":0.2909204147503886,"score_spread":0.2650970413291897,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}